| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 33 | 33 | 18 | 11 | 3.82 | .294 | 1.23 | 9.0 | 2.1 | 5.0 | 233.0 | 232 | 106 | 99 | 19 | 54 | 129 | 5 | 0 | 0 | 0 | 19 | 5 | 1 | 3.71 |
| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 32 | 32 | 15 | 10 | 2.84 | .290 | 1.20 | 7.1 | 3.7 | 5.6 | 212.1 | 167 | 70 | 67 | 13 | 88 | 131 | 5 | 0 | 0 | 3 | 23 | 5 | 0 | 3.88 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 32 | 32 | 17 | 6 | 3.57 | .302 | 1.28 | 8.5 | 3.0 | 7.7 | 217.0 | 206 | 88 | 86 | 20 | 72 | 186 | 1 | 0 | 0 | 0 | 21 | 3 | 5 | 3.52 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 77 | 31 | 31 | 12 | 10 | 5.06 | .319 | 1.39 | 9.3 | 3.3 | 6.4 | 201.0 | 207 | 113 | 113 | 21 | 73 | 142 | 2 | 0 | 0 | 0 | 13 | 3 | 5 | 4.08 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 68 | 0 | 4 | 7 | 2.13 | .209 | 0.74 | 5.1 | 1.5 | 7.9 | 72.0 | 41 | 18 | 17 | 7 | 12 | 63 | 0 | 51 | 2 | 0 | 0 | 4 | 0 | 3.18 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 51 | 0 | 2 | 3 | 4.14 | .315 | 1.34 | 8.1 | 4.0 | 7.9 | 50.0 | 45 | 23 | 23 | 3 | 22 | 44 | 0 | 0 | 1 | 0 | 0 | 2 | 3 | 3.46 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 25 | 0 | 1 | 0 | 3.42 | .290 | 1.23 | 9.0 | 2.3 | 6.3 | 23.2 | 23 | 11 | 9 | 2 | 6 | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.52 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 20 | 0 | 1 | 0 | 4.96 | .290 | 1.22 | 9.0 | 2.3 | 12.4 | 16.1 | 16 | 9 | 9 | 2 | 4 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.63 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 4 | 0 | 1 | 1 | 4.00 | .280 | 1.17 | 8.5 | 2.0 | 3.5 | 18.0 | 17 | 8 | 8 | 0 | 4 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.89 |