| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 33 | 33 | 14 | 9 | 3.82 | .302 | 1.28 | 8.4 | 3.1 | 4.5 | 226.0 | 212 | 103 | 96 | 18 | 77 | 112 | 4 | 0 | 0 | 1 | 21 | 4 | 3 | 4.12 |
| SP | Arrieta, J.Arrieta, Jake † # >> | 29 | 2015 | R | 93 | 32 | 32 | 16 | 10 | 3.35 | .268 | 1.09 | 7.6 | 2.2 | 7.6 | 206.2 | 175 | 82 | 77 | 11 | 50 | 173 | 5 | 0 | 0 | 5 | 20 | 2 | 4 | 2.77 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 32 | 32 | 11 | 7 | 4.28 | .309 | 1.32 | 9.2 | 2.7 | 3.5 | 208.0 | 212 | 110 | 99 | 17 | 62 | 81 | 4 | 0 | 0 | 2 | 17 | 5 | 3 | 4.25 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 33 | 31 | 14 | 12 | 4.58 | .328 | 1.44 | 9.4 | 3.6 | 4.4 | 208.1 | 218 | 112 | 106 | 23 | 83 | 102 | 6 | 0 | 0 | 0 | 12 | 4 | 6 | 4.71 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 67 | 0 | 3 | 3 | 3.46 | .309 | 1.34 | 7.9 | 4.2 | 9.1 | 65.0 | 57 | 26 | 25 | 4 | 30 | 66 | 0 | 3 | 0 | 0 | 0 | 0 | 4 | 3.15 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 76 | 0 | 6 | 2 | 2.70 | .263 | 1.07 | 5.6 | 4.0 | 9.7 | 83.1 | 52 | 30 | 25 | 8 | 37 | 89 | 0 | 40 | 6 | 0 | 0 | 0 | 0 | 3.45 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 43 | 0 | 5 | 1 | 2.54 | .242 | 0.91 | 5.1 | 3.1 | 6.3 | 46.0 | 26 | 13 | 13 | 1 | 16 | 32 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.07 |
| RP | Holland, G.Holland, Greg # >> | 27 | 2013 | R | 71 | 34 | 0 | 1 | 2 | 4.73 | .322 | 1.36 | 8.2 | 4.2 | 9.0 | 32.1 | 29 | 17 | 17 | 7 | 15 | 32 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.44 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 6 | 2 | 1 | 1 | 7.02 | .351 | 1.62 | 9.6 | 5.6 | 3.9 | 16.2 | 17 | 13 | 13 | 3 | 10 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.44 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 2 | 0 | 2 | 0 | 1.93 | .300 | 1.29 | 11.3 | 2.3 | 9.0 | 4.2 | 5 | 1 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.75 |