| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 16 | 16 | 5 | 5 | 2.96 | .267 | 1.08 | 7.9 | 1.9 | 9.1 | 121.2 | 106 | 53 | 40 | 14 | 25 | 122 | 2 | 0 | 0 | 0 | 11 | 2 | 1 | 3.16 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 16 | 16 | 9 | 1 | 2.86 | .275 | 1.12 | 6.4 | 3.7 | 5.6 | 107.0 | 76 | 38 | 34 | 5 | 44 | 67 | 0 | 0 | 0 | 0 | 13 | 2 | 0 | 3.64 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 16 | 16 | 10 | 4 | 3.53 | .279 | 1.13 | 7.8 | 2.5 | 5.2 | 109.2 | 94 | 47 | 43 | 13 | 30 | 63 | 1 | 0 | 0 | 0 | 11 | 3 | 1 | 4.30 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 16 | 16 | 4 | 5 | 7.62 | .366 | 1.68 | 10.2 | 5.0 | 7.7 | 78.0 | 88 | 66 | 66 | 12 | 43 | 67 | 1 | 0 | 0 | 1 | 6 | 4 | 1 | 5.09 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 16 | 16 | 8 | 5 | 4.02 | .337 | 1.52 | 11.1 | 2.6 | 4.7 | 107.1 | 132 | 66 | 48 | 19 | 31 | 56 | 2 | 0 | 0 | 0 | 11 | 1 | 1 | 5.16 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 29 | 0 | 0 | 1 | 4.18 | .354 | 1.64 | 6.8 | 8.0 | 11.6 | 28.0 | 21 | 13 | 13 | 1 | 25 | 36 | 0 | 20 | 4 | 0 | 0 | 0 | 1 | 3.57 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 41 | 0 | 5 | 3 | 4.42 | .276 | 1.15 | 8.0 | 2.5 | 10.5 | 36.2 | 32 | 20 | 18 | 3 | 10 | 42 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 2.58 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 29 | 0 | 3 | 0 | 3.77 | .331 | 1.48 | 10.2 | 3.2 | 9.3 | 31.0 | 35 | 13 | 13 | 4 | 11 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.68 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 18 | 0 | 2 | 1 | 4.42 | .313 | 1.36 | 10.0 | 2.5 | 9.5 | 18.1 | 20 | 9 | 9 | 2 | 5 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.17 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 3 | 0 | 1 | 1 | 6.23 | .350 | 1.62 | 13.5 | 2.3 | 4.5 | 4.1 | 6 | 3 | 3 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.25 |