| SP | Richard, J.Richard, J.R. # >> | 30 | 1980 | R | 90 | 32 | 32 | 15 | 7 | 3.61 | .315 | 1.36 | 7.9 | 4.3 | 8.6 | 194.2 | 171 | 85 | 78 | 12 | 93 | 185 | 0 | 0 | 0 | 0 | 19 | 5 | 1 | 3.41 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 76 | 32 | 32 | 14 | 13 | 4.46 | .304 | 1.28 | 9.3 | 2.3 | 5.9 | 218.0 | 225 | 116 | 108 | 25 | 55 | 142 | 8 | 0 | 0 | 2 | 17 | 5 | 6 | 4.01 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 31 | 31 | 10 | 8 | 4.21 | .327 | 1.44 | 7.8 | 5.2 | 8.5 | 192.1 | 166 | 103 | 90 | 20 | 110 | 181 | 1 | 0 | 0 | 0 | 17 | 4 | 3 | 4.25 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 60 | 0 | 4 | 4 | 4.47 | .303 | 1.27 | 9.7 | 1.8 | 9.2 | 54.1 | 58 | 27 | 27 | 6 | 11 | 55 | 0 | 41 | 10 | 0 | 0 | 2 | 3 | 3.13 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 63 | 0 | 3 | 4 | 4.35 | .331 | 1.48 | 7.7 | 5.7 | 10.4 | 60.0 | 51 | 32 | 29 | 4 | 38 | 69 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 3.47 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 70 | 0 | 4 | 3 | 3.94 | .317 | 1.38 | 7.4 | 5.1 | 5.8 | 77.2 | 63 | 38 | 34 | 12 | 44 | 50 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 5.48 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 44 | 0 | 4 | 2 | 2.16 | .279 | 1.16 | 6.8 | 3.6 | 7.7 | 50.0 | 38 | 15 | 12 | 6 | 20 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.04 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 34 | 0 | 1 | 0 | 2.77 | .287 | 1.18 | 7.4 | 3.2 | 8.3 | 39.0 | 32 | 12 | 12 | 2 | 14 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.97 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 37 | 0 | 2 | 1 | 2.90 | .316 | 1.36 | 9.2 | 3.2 | 5.6 | 40.1 | 41 | 16 | 13 | 3 | 14 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.85 |