| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 5 | 5 | 3 | 1 | 3.41 | .288 | 1.16 | 8.5 | 1.9 | 8.3 | 37.0 | 35 | 16 | 14 | 1 | 8 | 34 | 1 | 0 | 0 | 0 | 4 | 2 | 3 | 2.32 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 3 | 2 | 2 | 0 | 2.60 | .325 | 1.44 | 9.0 | 4.2 | 5.3 | 17.1 | 17 | 7 | 5 | 1 | 8 | 10 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.00 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 5 | 5 | 1 | 3 | 5.97 | .388 | 1.90 | 10.9 | 6.6 | 4.5 | 34.2 | 41 | 27 | 23 | 7 | 25 | 17 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 6.88 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 14 | 0 | 0 | 1 | 6.28 | .358 | 1.67 | 13.5 | 1.9 | 10.9 | 14.1 | 21 | 12 | 10 | 4 | 3 | 17 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 4.93 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 10 | 0 | 0 | 0 | 1.88 | .218 | 0.84 | 6.4 | 1.3 | 10.3 | 14.1 | 10 | 3 | 3 | 2 | 2 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 7 | 0 | 1 | 1 | 3.86 | .382 | 1.86 | 12.9 | 3.9 | 9.0 | 7.0 | 10 | 3 | 3 | 0 | 3 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.29 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 5 | 0 | 1 | 0 | 1.69 | .111 | 0.38 | 3.6 | 0.0 | 10.8 | 5.1 | 2 | 1 | 1 | 1 | 0 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.20 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 5 | 0 | 0 | 0 | 7.36 | .241 | 0.95 | 7.7 | 1.3 | 6.4 | 7.1 | 6 | 6 | 6 | 2 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.71 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 5 | 3 | 0 | 3 | 6.37 | .360 | 1.69 | 11.2 | 4.3 | 5.9 | 29.2 | 36 | 22 | 21 | 6 | 14 | 19 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5.83 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 3 | 3 | 0 | 3 | 5.40 | .420 | 2.18 | 15.9 | 4.2 | 6.9 | 13.1 | 23 | 13 | 8 | 4 | 6 | 10 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 6.85 |