| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 40 | 40 | 18 | 13 | 3.46 | .265 | 1.07 | 7.7 | 1.9 | 8.0 | 293.2 | 251 | 119 | 113 | 27 | 62 | 261 | 6 | 0 | 0 | 2 | 26 | 4 | 4 | 3.09 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 38 | 38 | 17 | 9 | 2.72 | .289 | 1.21 | 7.1 | 3.7 | 5.2 | 255.0 | 202 | 88 | 77 | 14 | 106 | 146 | 3 | 0 | 0 | 1 | 28 | 3 | 2 | 3.85 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 28 | 28 | 8 | 8 | 3.59 | .315 | 1.35 | 7.5 | 4.7 | 8.0 | 190.1 | 158 | 84 | 76 | 14 | 99 | 168 | 0 | 0 | 0 | 0 | 19 | 5 | 5 | 3.83 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 35 | 35 | 16 | 10 | 4.78 | .339 | 1.50 | 9.8 | 3.7 | 7.2 | 211.0 | 229 | 120 | 112 | 20 | 87 | 169 | 0 | 0 | 0 | 0 | 17 | 8 | 2 | 3.98 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 75 | 0 | 5 | 9 | 2.39 | .259 | 1.05 | 6.4 | 3.0 | 8.6 | 83.0 | 59 | 22 | 22 | 7 | 28 | 79 | 0 | 45 | 5 | 0 | 0 | 0 | 0 | 3.20 |
| SU | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 56 | 0 | 3 | 3 | 3.29 | .257 | 1.02 | 6.5 | 2.8 | 7.3 | 65.2 | 47 | 25 | 24 | 4 | 20 | 53 | 0 | 6 | 4 | 0 | 0 | 1 | 3 | 3.14 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 68 | 0 | 5 | 3 | 3.09 | .308 | 1.32 | 7.0 | 5.0 | 7.5 | 78.2 | 61 | 31 | 27 | 8 | 43 | 65 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 4.36 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 71 | 0 | 4 | 5 | 4.27 | .317 | 1.40 | 9.1 | 3.5 | 8.1 | 71.2 | 72 | 35 | 34 | 8 | 28 | 64 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.85 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 50 | 0 | 4 | 4 | 4.12 | .325 | 1.42 | 8.0 | 5.0 | 6.5 | 43.2 | 38 | 23 | 20 | 3 | 24 | 31 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 4.21 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 11 | 0 | 0 | 1 | 2.70 | .231 | 0.90 | 6.0 | 3.0 | 9.0 | 6.2 | 4 | 2 | 2 | 1 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 14 | 0 | 0 | 0 | 4.86 | .296 | 1.20 | 8.4 | 2.8 | 7.3 | 16.2 | 15 | 10 | 9 | 2 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.13 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 10 | 9 | 2 | 4 | 5.63 | .300 | 1.27 | 9.6 | 1.8 | 7.1 | 56.0 | 60 | 35 | 35 | 10 | 11 | 44 | 2 | 0 | 0 | 0 | 3 | 1 | 0 | 4.39 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 10 | 0 | 0 | 2 | 4.17 | .288 | 1.21 | 6.8 | 4.2 | 6.4 | 45.1 | 34 | 22 | 21 | 3 | 21 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 3.84 |