| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 18 | 18 | 7 | 7 | 5.12 | .319 | 1.41 | 9.9 | 2.8 | 8.5 | 123.0 | 135 | 71 | 70 | 23 | 38 | 116 | 5 | 0 | 0 | 1 | 7 | 0 | 2 | 4.47 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 18 | 18 | 5 | 7 | 5.87 | .329 | 1.46 | 10.0 | 3.2 | 5.1 | 110.1 | 122 | 77 | 72 | 16 | 39 | 62 | 1 | 0 | 0 | 0 | 7 | 1 | 0 | 4.85 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 17 | 17 | 10 | 7 | 5.17 | .318 | 1.39 | 10.2 | 2.4 | 6.1 | 116.2 | 131 | 67 | 67 | 16 | 31 | 78 | 2 | 0 | 0 | 0 | 6 | 1 | 1 | 4.28 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 46 | 0 | 0 | 5 | 5.10 | .321 | 1.37 | 8.7 | 3.6 | 9.3 | 60.0 | 58 | 35 | 34 | 12 | 24 | 62 | 0 | 3 | 3 | 0 | 0 | 3 | 1 | 4.88 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 41 | 0 | 1 | 1 | 2.72 | .296 | 1.21 | 8.8 | 2.0 | 7.6 | 53.0 | 52 | 18 | 16 | 1 | 12 | 45 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 2.40 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 38 | 0 | 2 | 3 | 5.17 | .324 | 1.43 | 10.7 | 2.4 | 8.8 | 38.1 | 45 | 28 | 22 | 7 | 10 | 37 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 4.24 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 27 | 0 | 2 | 1 | 3.41 | .279 | 1.14 | 6.6 | 3.6 | 5.1 | 37.0 | 27 | 14 | 14 | 4 | 15 | 21 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.57 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 1 | 0 | 0 | 0 | 10.13 | .529 | 3.38 | 27.0 | 13.5 | 9.0 | 2.2 | 6 | 4 | 3 | 1 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 12.00 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 18 | 0 | 3 | 0 | 3.98 | .371 | 1.72 | 8.6 | 7.2 | 10.4 | 20.1 | 19 | 9 | 9 | 1 | 16 | 23 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.90 |