| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 88 | 13 | 13 | 5 | 7 | 3.98 | .296 | 1.26 | 8.0 | 3.4 | 7.5 | 74.2 | 66 | 34 | 33 | 8 | 28 | 62 | 1 | 0 | 0 | 1 | 8 | 0 | 0 | 3.86 |
| SP | Tejeda, R.Tejeda, Robinson >> | 26 | 2005 | R | 67 | 13 | 13 | 0 | 4 | 4.86 | .324 | 1.40 | 9.2 | 3.4 | 7.4 | 50.0 | 51 | 29 | 27 | 5 | 19 | 41 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.92 |
| RP | Madson, R.Madson, Ryan >> | 28 | 2004 | R | 64 | 35 | 0 | 3 | 3 | 3.95 | .301 | 1.29 | 9.0 | 2.6 | 5.5 | 41.0 | 41 | 20 | 18 | 4 | 12 | 25 | 0 | 0 | 2 | 0 | 0 | 0 | 6 | 3.93 |
| RP | Cormier, R.Cormier, Rheal >> | 41 | 2003 | L | 51 | 37 | 0 | 1 | 2 | 4.91 | .345 | 1.58 | 10.5 | 4.0 | 7.0 | 18.1 | 21 | 10 | 10 | 3 | 8 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.94 |
| RP | Durbin, C.Durbin, Chad >> | 31 | 2008 | R | 26 | 26 | 0 | 1 | 1 | 4.03 | .310 | 1.31 | 6.8 | 5.0 | 6.5 | 29.0 | 22 | 13 | 13 | 3 | 16 | 21 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.66 |
| CL | de los Santos, V.de los Santos, Valerio >> | 36 | 2003 | L | 11 | 21 | 0 | 0 | 2 | 6.30 | .355 | 1.65 | 9.5 | 5.4 | 7.7 | 20.0 | 21 | 17 | 14 | 2 | 12 | 17 | 0 | 14 | 3 | 0 | 0 | 0 | 2 | 4.40 |
| RP | Seanez, R.Seanez, Rudy >> | 40 | 2008 | R | 18 | 15 | 0 | 1 | 0 | 2.65 | .250 | 1.00 | 5.3 | 3.7 | 5.8 | 17.0 | 10 | 5 | 5 | 1 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.71 |
| SP | Millwood, K.Millwood, Kevin >> | 34 | 2003 | R | 42 | 16 | 0 | 2 | 1 | 5.55 | .321 | 1.40 | 8.1 | 4.7 | 6.2 | 48.2 | 43 | 31 | 30 | 7 | 25 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.15 |