| SP | Clemens, R.Clemens, Roger >> | 46 | 2005 | R | 93 | 13 | 13 | 5 | 5 | 4.37 | .336 | 1.47 | 9.7 | 3.6 | 6.4 | 80.1 | 86 | 45 | 39 | 9 | 32 | 57 | 0 | 0 | 0 | 0 | 6 | 4 | 2 | 4.39 |
| SP | Pettitte, A.Pettitte, Andy >> | 36 | 2005 | L | 80 | 12 | 12 | 3 | 4 | 4.30 | .331 | 1.47 | 10.5 | 2.8 | 5.8 | 73.1 | 85 | 37 | 35 | 5 | 23 | 47 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 3.59 |
| SP | Vazquez, J.Vazquez, Javier >> | 32 | 2007 | R | 73 | 12 | 12 | 6 | 4 | 4.00 | .338 | 1.48 | 9.6 | 3.8 | 6.7 | 81.0 | 86 | 47 | 36 | 9 | 34 | 60 | 1 | 0 | 0 | 0 | 5 | 4 | 2 | 4.37 |
| SP | Wang, C.Wang, Chien-Ming >> | 28 | 2005 | R | 72 | 12 | 12 | 5 | 3 | 3.88 | .286 | 1.15 | 9.1 | 1.2 | 5.4 | 65.0 | 66 | 29 | 28 | 7 | 9 | 39 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 3.75 |
| SP | Harang, A.Harang, Aaron >> | 30 | 2007 | R | 69 | 12 | 12 | 4 | 1 | 3.92 | .309 | 1.31 | 8.5 | 3.3 | 6.9 | 57.1 | 54 | 31 | 25 | 8 | 21 | 44 | 0 | 0 | 0 | 0 | 5 | 2 | 2 | 4.49 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 99 | 35 | 0 | 0 | 0 | 3.55 | .288 | 1.16 | 8.8 | 1.7 | 13.0 | 38.0 | 37 | 16 | 15 | 3 | 7 | 55 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 1.84 |
| RP | Marte, D.Marte, Damaso >> | 33 | 2008 | L | 64 | 37 | 0 | 3 | 0 | 4.50 | .333 | 1.44 | 8.0 | 5.0 | 11.0 | 18.0 | 16 | 9 | 9 | 4 | 10 | 22 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 5.28 |
| RP | Ramirez, E.Ramirez, Edwar >> | 27 | 2008 | R | 61 | 25 | 0 | 1 | 1 | 4.03 | .256 | 1.03 | 5.3 | 4.1 | 8.2 | 22.1 | 13 | 10 | 10 | 2 | 10 | 20 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.73 |
| RP | Heredia, F.Heredia, Felix >> | 33 | 2003 | L | 52 | 23 | 0 | 1 | 2 | 5.74 | .329 | 1.47 | 9.6 | 4.2 | 6.6 | 15.2 | 16 | 10 | 10 | 3 | 7 | 11 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 5.53 |
| RP | Chamberlain, J.Chamberlain, Joba >> | 23 | 2008 | R | 44 | 21 | 0 | 1 | 2 | 2.81 | .325 | 1.44 | 10.4 | 2.9 | 9.7 | 25.2 | 29 | 10 | 8 | 3 | 8 | 27 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.36 |
| SP | Johnson, R.Johnson, Randy >> | 45 | 2005 | L | 55 | 12 | 0 | 2 | 4 | 3.54 | .293 | 1.18 | 7.5 | 3.2 | 6.2 | 48.1 | 40 | 20 | 19 | 3 | 17 | 33 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 3.69 |