| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 8 | 8 | 3 | 5 | 5.27 | .317 | 1.39 | 9.3 | 3.3 | 7.2 | 54.2 | 56 | 36 | 32 | 11 | 20 | 43 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 5.17 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 8 | 8 | 3 | 3 | 2.93 | .300 | 1.27 | 8.7 | 2.8 | 6.6 | 61.1 | 59 | 27 | 20 | 6 | 19 | 45 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 3.79 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 7 | 7 | 1 | 4 | 8.68 | .374 | 1.79 | 12.6 | 3.6 | 3.9 | 37.1 | 52 | 38 | 36 | 12 | 15 | 16 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 7.57 |
| SP | Carpenter, C.Carpenter, Chris >> | 30 | 2005 | R | 21 | 7 | 7 | 2 | 2 | 6.97 | .380 | 1.81 | 13.9 | 2.3 | 6.7 | 31.0 | 48 | 24 | 24 | 3 | 8 | 23 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 3.65 |
| SP | Taylor, J.Taylor, Jack >> | 28 | 1902 | R | 39 | 8 | 7 | 3 | 2 | 3.36 | .290 | 1.15 | 8.4 | 2.1 | 3.9 | 56.1 | 52 | 23 | 21 | 2 | 13 | 24 | 2 | 0 | 0 | 0 | 4 | 4 | 2 | 3.52 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 12 | 0 | 0 | 0 | 3.38 | .310 | 1.35 | 9.0 | 3.5 | 6.2 | 13.1 | 13 | 8 | 5 | 1 | 5 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.77 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 13 | 0 | 0 | 0 | 1.23 | .343 | 1.50 | 10.3 | 3.9 | 8.4 | 14.2 | 16 | 2 | 2 | 1 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.57 |
| SU | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 18 | 0 | 2 | 1 | 6.63 | .374 | 1.74 | 9.9 | 5.7 | 9.0 | 19.0 | 21 | 14 | 14 | 3 | 12 | 19 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 5.11 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 18 | 0 | 0 | 2 | 5.68 | .345 | 1.58 | 11.3 | 3.8 | 12.8 | 12.2 | 15 | 8 | 8 | 2 | 5 | 17 | 0 | 9 | 3 | 0 | 0 | 0 | 0 | 3.58 |