| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 19 | 19 | 6 | 8 | 3.30 | .263 | 1.06 | 6.9 | 2.6 | 9.8 | 131.0 | 101 | 50 | 48 | 14 | 38 | 142 | 2 | 0 | 0 | 2 | 12 | 1 | 0 | 3.11 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 75 | 18 | 18 | 5 | 10 | 6.13 | .368 | 1.70 | 10.9 | 4.5 | 5.8 | 111.2 | 134 | 92 | 76 | 15 | 56 | 71 | 3 | 0 | 0 | 1 | 5 | 5 | 2 | 5.13 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 17 | 17 | 6 | 7 | 4.33 | .347 | 1.53 | 8.0 | 5.8 | 8.2 | 97.2 | 86 | 51 | 47 | 6 | 63 | 88 | 0 | 0 | 0 | 0 | 6 | 7 | 2 | 4.15 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 54 | 18 | 17 | 4 | 8 | 6.19 | .365 | 1.69 | 10.7 | 4.6 | 6.4 | 88.2 | 105 | 64 | 61 | 16 | 45 | 63 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 5.57 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 42 | 19 | 17 | 4 | 10 | 5.21 | .336 | 1.50 | 10.1 | 3.4 | 4.7 | 114.0 | 128 | 70 | 66 | 15 | 43 | 59 | 1 | 1 | 0 | 0 | 7 | 2 | 2 | 4.86 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 51 | 0 | 2 | 2 | 4.07 | .277 | 1.14 | 6.2 | 4.1 | 7.4 | 73.0 | 50 | 34 | 33 | 13 | 33 | 60 | 0 | 4 | 3 | 0 | 0 | 1 | 3 | 5.07 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 48 | 0 | 3 | 3 | 5.52 | .310 | 1.35 | 7.3 | 5.0 | 8.1 | 58.2 | 47 | 36 | 36 | 7 | 32 | 52 | 0 | 6 | 1 | 0 | 0 | 0 | 5 | 4.43 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 25 | 0 | 1 | 2 | 5.73 | .365 | 1.70 | 9.5 | 6.1 | 8.5 | 37.2 | 39 | 27 | 24 | 3 | 25 | 35 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.27 |