| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 19 | 19 | 9 | 8 | 3.57 | .256 | 1.02 | 7.6 | 1.6 | 7.9 | 138.2 | 116 | 55 | 55 | 12 | 25 | 121 | 3 | 0 | 0 | 0 | 10 | 2 | 6 | 2.96 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 18 | 18 | 5 | 8 | 5.12 | .308 | 1.29 | 8.8 | 2.8 | 8.0 | 116.0 | 114 | 72 | 66 | 15 | 36 | 103 | 0 | 0 | 0 | 0 | 8 | 5 | 2 | 3.97 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 17 | 17 | 10 | 5 | 3.50 | .266 | 1.06 | 7.4 | 2.2 | 5.6 | 133.2 | 110 | 55 | 52 | 10 | 32 | 83 | 7 | 0 | 0 | 1 | 11 | 3 | 3 | 3.52 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 68 | 17 | 17 | 4 | 10 | 5.38 | .335 | 1.51 | 10.3 | 3.3 | 5.1 | 112.0 | 128 | 72 | 67 | 18 | 41 | 63 | 2 | 0 | 0 | 0 | 8 | 0 | 4 | 5.06 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 66 | 16 | 15 | 6 | 6 | 4.86 | .333 | 1.48 | 10.0 | 3.4 | 3.9 | 103.2 | 114 | 61 | 56 | 13 | 39 | 45 | 5 | 0 | 0 | 1 | 6 | 2 | 3 | 4.96 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 34 | 0 | 1 | 4 | 5.67 | .339 | 1.49 | 8.8 | 4.8 | 9.7 | 39.2 | 38 | 25 | 25 | 7 | 21 | 42 | 0 | 5 | 2 | 0 | 0 | 2 | 1 | 4.95 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 24 | 0 | 1 | 0 | 2.97 | .254 | 0.96 | 6.9 | 1.8 | 7.2 | 30.1 | 23 | 10 | 10 | 2 | 6 | 24 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.07 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 13 | 0 | 0 | 3 | 6.23 | .391 | 1.85 | 11.8 | 4.8 | 12.5 | 13.0 | 17 | 9 | 9 | 3 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.08 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 53 | 19 | 0 | 0 | 1 | 6.41 | .306 | 1.22 | 10.9 | 0.5 | 7.6 | 19.2 | 23 | 14 | 14 | 4 | 1 | 16 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.53 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 65 | 2 | 2 | 1 | 1 | 4.63 | .286 | 1.20 | 8.2 | 3.3 | 0.0 | 11.2 | 10 | 6 | 6 | 2 | 4 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6.45 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 5 | 0 | 0 | 1 | 9.00 | .385 | 1.88 | 14.6 | 2.3 | 9.0 | 8.0 | 13 | 8 | 8 | 4 | 2 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 8.25 |