| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 19 | 19 | 10 | 8 | 3.48 | .289 | 1.18 | 7.2 | 3.5 | 7.3 | 134.1 | 107 | 63 | 52 | 18 | 52 | 108 | 4 | 0 | 0 | 1 | 13 | 5 | 1 | 4.41 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 18 | 18 | 8 | 5 | 3.02 | .283 | 1.16 | 8.2 | 2.3 | 3.2 | 128.1 | 116 | 51 | 43 | 7 | 33 | 45 | 3 | 0 | 0 | 1 | 13 | 3 | 2 | 3.85 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 17 | 17 | 5 | 9 | 6.15 | .350 | 1.59 | 10.3 | 4.1 | 5.8 | 105.1 | 120 | 76 | 72 | 12 | 48 | 68 | 2 | 0 | 0 | 0 | 6 | 2 | 2 | 4.62 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 36 | 0 | 1 | 1 | 2.78 | .282 | 1.18 | 5.1 | 5.7 | 8.5 | 35.2 | 20 | 11 | 11 | 3 | 22 | 33 | 0 | 26 | 4 | 0 | 0 | 0 | 0 | 4.11 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 36 | 0 | 1 | 1 | 2.50 | .287 | 1.18 | 6.7 | 4.2 | 6.7 | 39.2 | 29 | 11 | 11 | 2 | 18 | 29 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.64 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 18 | 0 | 1 | 2 | 4.43 | .330 | 1.43 | 9.0 | 4.1 | 8.1 | 20.1 | 20 | 10 | 10 | 2 | 9 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 13 | 0 | 0 | 1 | 4.80 | .318 | 1.40 | 9.6 | 3.0 | 9.0 | 15.0 | 16 | 9 | 8 | 2 | 5 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.73 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 7 | 0 | 1 | 0 | 5.63 | .351 | 1.63 | 7.9 | 6.8 | 6.8 | 8.0 | 7 | 5 | 5 | 1 | 6 | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.38 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 19 | 0 | 0 | 0 | 6.85 | .366 | 1.73 | 12.1 | 3.9 | 9.8 | 23.2 | 31 | 21 | 18 | 2 | 10 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.26 |