| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 26 | 26 | 11 | 12 | 4.31 | .285 | 1.17 | 7.9 | 2.6 | 9.1 | 198.1 | 174 | 101 | 95 | 22 | 58 | 200 | 11 | 0 | 0 | 2 | 12 | 5 | 3 | 3.38 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 25 | 25 | 14 | 3 | 3.12 | .296 | 1.23 | 7.6 | 3.4 | 6.1 | 173.1 | 147 | 67 | 60 | 11 | 66 | 118 | 1 | 0 | 0 | 1 | 17 | 6 | 0 | 3.71 |
| SP | Guidry, R.Guidry, Ron † >> | 28 | 1978 | L | 78 | 24 | 24 | 11 | 8 | 3.62 | .302 | 1.28 | 8.2 | 3.3 | 6.2 | 166.2 | 152 | 72 | 67 | 24 | 61 | 114 | 5 | 0 | 0 | 1 | 15 | 3 | 2 | 4.66 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 64 | 0 | 8 | 6 | 3.12 | .283 | 1.17 | 5.8 | 4.8 | 7.8 | 95.1 | 61 | 38 | 33 | 12 | 51 | 82 | 0 | 6 | 5 | 0 | 0 | 1 | 0 | 4.56 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 27 | 0 | 2 | 0 | 3.19 | .244 | 0.97 | 7.0 | 1.7 | 9.3 | 31.0 | 24 | 11 | 11 | 2 | 6 | 32 | 0 | 7 | 1 | 0 | 0 | 0 | 1 | 2.35 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 13 | 0 | 2 | 1 | 3.55 | .377 | 1.82 | 9.0 | 8.3 | 9.0 | 12.2 | 12 | 5 | 5 | 1 | 11 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.83 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 16 | 0 | 0 | 0 | 0.55 | .269 | 1.04 | 3.4 | 6.2 | 8.4 | 16.1 | 6 | 3 | 1 | 1 | 11 | 15 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.19 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 15 | 0 | 1 | 2 | 7.31 | .377 | 1.81 | 12.9 | 3.4 | 6.2 | 16.0 | 23 | 14 | 13 | 3 | 6 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.19 |