| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 88 | 5 | 5 | 2 | 2 | 5.58 | .343 | 1.53 | 10.5 | 3.6 | 10.2 | 30.2 | 35 | 19 | 19 | 5 | 12 | 34 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.20 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 75 | 5 | 5 | 2 | 2 | 4.41 | .300 | 1.26 | 8.4 | 3.1 | 9.3 | 32.2 | 30 | 19 | 16 | 6 | 11 | 33 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.50 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 65 | 5 | 5 | 3 | 1 | 5.86 | .336 | 1.48 | 11.0 | 2.7 | 6.3 | 27.2 | 33 | 18 | 18 | 6 | 8 | 19 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.48 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 51 | 5 | 5 | 2 | 3 | 4.97 | .331 | 1.48 | 10.9 | 2.5 | 5.9 | 29.0 | 35 | 16 | 16 | 5 | 8 | 19 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.76 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 73 | 12 | 0 | 0 | 0 | 3.72 | .293 | 1.24 | 11.0 | 1.0 | 11.0 | 9.2 | 11 | 4 | 4 | 3 | 1 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.22 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 38 | 8 | 0 | 0 | 0 | 4.15 | .381 | 1.85 | 11.3 | 6.8 | 0.0 | 4.1 | 5 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.25 |
| RP | Shields, S.Shields, Scot >> | 30 | 2005 | R | 27 | 10 | 0 | 1 | 1 | 6.48 | .390 | 1.92 | 9.0 | 9.0 | 7.9 | 8.1 | 8 | 6 | 6 | 1 | 8 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.88 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 52 | 8 | 0 | 0 | 0 | 9.00 | .400 | 2.00 | 15.4 | 2.6 | 5.1 | 7.0 | 12 | 7 | 7 | 2 | 2 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.43 |