| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 33 | 33 | 12 | 8 | 3.79 | .316 | 1.37 | 8.6 | 3.7 | 9.6 | 221.0 | 211 | 95 | 93 | 23 | 92 | 236 | 1 | 0 | 0 | 1 | 19 | 3 | 9 | 3.51 |
| SP | Lowe, D.Lowe, Derek † $$ >> | 29 | 2002 | R | 90 | 32 | 32 | 17 | 8 | 3.05 | .272 | 1.11 | 7.2 | 2.7 | 5.6 | 227.0 | 182 | 88 | 77 | 25 | 69 | 140 | 5 | 0 | 0 | 1 | 23 | 4 | 4 | 4.16 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 71 | 32 | 32 | 9 | 14 | 5.11 | .349 | 1.59 | 9.9 | 4.5 | 7.1 | 195.2 | 215 | 118 | 111 | 29 | 97 | 153 | 1 | 0 | 0 | 0 | 15 | 3 | 3 | 4.90 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 54 | 31 | 31 | 13 | 9 | 4.52 | .327 | 1.43 | 10.1 | 2.8 | 8.0 | 181.1 | 203 | 94 | 91 | 27 | 56 | 160 | 0 | 0 | 0 | 0 | 15 | 5 | 10 | 4.18 |
| CL | Papelbon, J.Papelbon, Jonathan † $$ >> | 26 | 2006 | R | 94 | 65 | 0 | 7 | 9 | 3.69 | .271 | 1.09 | 7.6 | 2.3 | 9.3 | 70.2 | 59 | 29 | 29 | 7 | 18 | 72 | 0 | 36 | 5 | 0 | 0 | 2 | 1 | 3.10 |
| SU | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 65 | 0 | 6 | 4 | 4.07 | .291 | 1.18 | 6.9 | 3.7 | 6.9 | 77.1 | 59 | 38 | 35 | 11 | 32 | 59 | 0 | 3 | 6 | 0 | 0 | 4 | 1 | 4.73 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 85 | 86 | 0 | 7 | 4 | 3.88 | .308 | 1.28 | 8.6 | 3.0 | 5.6 | 99.2 | 95 | 48 | 43 | 13 | 33 | 62 | 0 | 5 | 8 | 0 | 0 | 5 | 7 | 4.61 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 60 | 0 | 3 | 0 | 5.37 | .343 | 1.54 | 10.2 | 3.7 | 8.5 | 70.1 | 79 | 46 | 42 | 16 | 29 | 66 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 5.41 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 69 | 48 | 0 | 2 | 2 | 2.92 | .264 | 1.05 | 6.2 | 3.3 | 9.4 | 49.1 | 34 | 16 | 16 | 5 | 18 | 51 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.41 |