| SP | Lincecum, T.Lincecum, Tim $ >> | 25 | 2009 | R | 92 | 18 | 18 | 4 | 8 | 4.36 | .329 | 1.42 | 8.7 | 4.1 | 10.5 | 115.2 | 111 | 61 | 56 | 15 | 53 | 134 | 0 | 0 | 0 | 0 | 11 | 6 | 7 | 3.90 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 17 | 17 | 6 | 5 | 5.13 | .333 | 1.44 | 10.2 | 2.9 | 6.7 | 101.2 | 114 | 66 | 58 | 14 | 32 | 75 | 0 | 0 | 0 | 0 | 9 | 6 | 2 | 4.45 |
| SP | Loaiza, E.Loaiza, Esteban † >> | 32 | 2003 | R | 60 | 17 | 17 | 10 | 2 | 3.79 | .325 | 1.41 | 9.2 | 3.6 | 6.8 | 111.2 | 113 | 52 | 47 | 15 | 45 | 84 | 0 | 0 | 0 | 0 | 11 | 3 | 1 | 4.54 |
| CL | Papelbon, J.Papelbon, Jonathan † $ >> | 26 | 2006 | R | 94 | 38 | 0 | 2 | 5 | 4.22 | .304 | 1.29 | 9.6 | 2.1 | 8.8 | 42.2 | 45 | 21 | 20 | 6 | 10 | 41 | 0 | 20 | 1 | 0 | 0 | 1 | 1 | 3.69 |
| SU | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 42 | 0 | 0 | 2 | 3.70 | .315 | 1.36 | 8.1 | 4.3 | 11.1 | 48.2 | 43 | 20 | 20 | 5 | 23 | 59 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 3.40 |
| RP | Foulke, K.Foulke, Keith † >> | 31 | 2003 | R | 78 | 51 | 0 | 6 | 1 | 2.84 | .314 | 1.31 | 8.8 | 3.1 | 8.6 | 44.1 | 43 | 15 | 14 | 6 | 15 | 42 | 0 | 2 | 2 | 0 | 0 | 3 | 0 | 4.09 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 49 | 0 | 3 | 0 | 3.82 | .280 | 1.14 | 7.1 | 3.4 | 10.0 | 37.2 | 29 | 17 | 16 | 8 | 14 | 41 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 4.81 |