| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 98 | 38 | 38 | 20 | 9 | 3.36 | .287 | 1.18 | 7.6 | 3.0 | 10.2 | 249.0 | 211 | 95 | 93 | 24 | 84 | 283 | 1 | 0 | 0 | 1 | 25 | 6 | 6 | 3.06 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 84 | 36 | 36 | 11 | 14 | 4.93 | .340 | 1.53 | 10.7 | 3.2 | 7.5 | 200.2 | 237 | 112 | 110 | 32 | 71 | 166 | 0 | 0 | 0 | 0 | 15 | 2 | 2 | 4.52 |
| SP | Giolito, L.Giolito, Lucas # >> | 24 | 2019 | R | 71 | 35 | 35 | 12 | 10 | 5.06 | .327 | 1.44 | 9.1 | 3.8 | 11.0 | 192.0 | 194 | 109 | 108 | 27 | 82 | 235 | 0 | 0 | 0 | 0 | 18 | 4 | 5 | 3.72 |
| SP | McHugh, C.McHugh, Collin >> | 27 | 2014 | R | 78 | 35 | 34 | 16 | 12 | 4.61 | .311 | 1.33 | 8.9 | 3.1 | 9.0 | 197.1 | 194 | 104 | 101 | 27 | 68 | 197 | 0 | 0 | 0 | 0 | 19 | 5 | 5 | 3.89 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 96 | 0 | 6 | 10 | 3.27 | .288 | 1.20 | 7.9 | 3.0 | 8.7 | 104.2 | 91 | 41 | 38 | 15 | 35 | 100 | 0 | 42 | 8 | 0 | 0 | 1 | 2 | 3.99 |
| RP | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 85 | 98 | 0 | 5 | 1 | 3.41 | .319 | 1.37 | 6.8 | 5.5 | 10.5 | 103.0 | 78 | 45 | 39 | 12 | 63 | 120 | 0 | 2 | 3 | 0 | 0 | 4 | 4 | 4.14 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 93 | 0 | 11 | 1 | 3.38 | .286 | 1.19 | 7.2 | 3.5 | 10.4 | 104.0 | 83 | 41 | 39 | 10 | 41 | 120 | 0 | 4 | 3 | 0 | 0 | 1 | 8 | 3.15 |
| RP | Siegrist, K.Siegrist, Kevin >> | 23 | 2013 | L | 79 | 74 | 0 | 3 | 0 | 3.95 | .322 | 1.38 | 6.4 | 6.0 | 11.0 | 73.0 | 52 | 34 | 32 | 5 | 49 | 89 | 0 | 4 | 0 | 0 | 0 | 3 | 0 | 3.59 |
| SP | Castillo, L.Castillo, Luis >> | 26 | 2019 | R | 50 | 30 | 0 | 5 | 3 | 8.07 | .401 | 1.98 | 12.1 | 5.9 | 9.4 | 64.2 | 86 | 61 | 58 | 15 | 42 | 67 | 0 | 4 | 0 | 0 | 0 | 2 | 2 | 6.02 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 75 | 114 | 0 | 5 | 1 | 3.91 | .270 | 1.10 | 7.0 | 3.0 | 9.2 | 103.2 | 80 | 48 | 45 | 14 | 34 | 105 | 0 | 2 | 3 | 0 | 0 | 1 | 2 | 3.75 |