| SP | Buchholz, C.Buchholz, Clay >> | 34 | 2018 | R | 43 | 12 | 12 | 5 | 7 | 4.01 | .300 | 1.27 | 8.1 | 3.3 | 6.7 | 74.0 | 67 | 36 | 33 | 8 | 27 | 55 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.05 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 41 | 12 | 12 | 5 | 4 | 3.08 | .300 | 1.29 | 8.4 | 3.2 | 6.6 | 61.1 | 57 | 21 | 21 | 6 | 22 | 45 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 3.89 |
| SP | Kelly, M.Kelly, Merrill # >> | 33 | 2022 | R | 34 | 12 | 12 | 2 | 7 | 5.37 | .313 | 1.35 | 8.6 | 3.7 | 6.0 | 68.2 | 65 | 42 | 41 | 8 | 28 | 45 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 4.49 |
| SP | Johnson, R.Johnson, Randy >> | 45 | 2008 | L | 31 | 13 | 12 | 4 | 4 | 6.44 | .367 | 1.69 | 12.0 | 3.4 | 7.3 | 64.1 | 85 | 46 | 46 | 10 | 24 | 52 | 1 | 0 | 0 | 1 | 3 | 3 | 2 | 4.67 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 48 | 37 | 0 | 0 | 2 | 5.47 | .331 | 1.48 | 8.3 | 5.2 | 8.7 | 52.2 | 48 | 32 | 32 | 8 | 30 | 50 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.81 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 43 | 35 | 0 | 2 | 1 | 3.05 | .303 | 1.28 | 7.9 | 3.7 | 4.8 | 41.1 | 36 | 14 | 14 | 3 | 17 | 22 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.20 |
| RP | Bradley, A.Bradley, Archie >> | 24 | 2017 | R | 36 | 30 | 0 | 1 | 0 | 3.53 | .290 | 1.22 | 6.9 | 4.2 | 10.0 | 43.1 | 33 | 17 | 17 | 5 | 20 | 48 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Valverde, J.Valverde, Jose >> | 28 | 2007 | R | 33 | 24 | 0 | 1 | 0 | 6.10 | .290 | 1.23 | 7.3 | 3.8 | 8.4 | 31.0 | 25 | 21 | 21 | 5 | 13 | 29 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.48 |
| RP | Villarreal, O.Villarreal, Oscar >> | 22 | 2003 | R | 22 | 25 | 0 | 1 | 1 | 5.22 | .323 | 1.40 | 9.6 | 3.1 | 5.6 | 29.1 | 31 | 17 | 17 | 6 | 10 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.59 |