| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 96 | 12 | 12 | 5 | 4 | 4.31 | .310 | 1.35 | 9.6 | 2.6 | 10.4 | 79.1 | 84 | 40 | 38 | 6 | 23 | 91 | 2 | 0 | 0 | 0 | 6 | 0 | 2 | 2.56 |
| SP | Buchholz, C.Buchholz, Clay # >> | 29 | 2013 | R | 81 | 12 | 12 | 6 | 3 | 4.72 | .328 | 1.44 | 9.1 | 3.8 | 7.2 | 82.0 | 83 | 44 | 43 | 12 | 35 | 66 | 1 | 0 | 0 | 0 | 5 | 2 | 4 | 4.65 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 79 | 12 | 12 | 4 | 5 | 5.38 | .323 | 1.43 | 8.4 | 4.5 | 10.4 | 72.0 | 67 | 45 | 43 | 12 | 36 | 83 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 4.36 |
| SP | Castillo, L.Castillo, Luis >> | 26 | 2019 | R | 49 | 11 | 11 | 3 | 4 | 7.76 | .398 | 1.95 | 12.7 | 4.8 | 9.8 | 58.0 | 82 | 52 | 50 | 9 | 31 | 63 | 0 | 0 | 0 | 0 | 3 | 2 | 4 | 4.55 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 80 | 27 | 0 | 2 | 2 | 5.66 | .352 | 1.60 | 8.5 | 5.9 | 12.1 | 35.0 | 33 | 22 | 22 | 8 | 23 | 47 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 5.34 |
| RP | Feliz, N.Feliz, Neftali >> | 22 | 2010 | R | 64 | 23 | 0 | 1 | 2 | 5.47 | .333 | 1.50 | 8.3 | 5.6 | 8.6 | 24.2 | 22 | 15 | 15 | 7 | 15 | 23 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 6.75 |
| RP | Devenski, C.Devenski, Chris >> | 26 | 2017 | R | 48 | 21 | 0 | 1 | 1 | 5.93 | .295 | 1.22 | 7.8 | 3.3 | 10.2 | 30.1 | 26 | 22 | 20 | 4 | 11 | 34 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 3.67 |
| RP | Neris, H.Neris, Hector >> | 30 | 2019 | R | 36 | 16 | 0 | 3 | 2 | 4.26 | .374 | 1.79 | 9.5 | 6.6 | 10.4 | 19.0 | 20 | 9 | 9 | 1 | 14 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.58 |
| SP | Johnson, J.Johnson, Josh >> | 26 | 2010 | R | 37 | 14 | 0 | 0 | 1 | 9.19 | .347 | 1.60 | 13.2 | 1.8 | 10.2 | 15.2 | 22 | 16 | 16 | 3 | 3 | 17 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.93 |