| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 99 | 13 | 13 | 1 | 3 | 4.88 | .312 | 1.33 | 8.1 | 3.9 | 10.0 | 72.0 | 65 | 40 | 39 | 9 | 31 | 80 | 1 | 0 | 0 | 1 | 4 | 2 | 2 | 3.78 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 13 | 13 | 5 | 7 | 4.73 | .346 | 1.55 | 10.5 | 3.5 | 8.6 | 72.1 | 84 | 48 | 38 | 13 | 28 | 69 | 1 | 0 | 0 | 1 | 6 | 3 | 5 | 4.72 |
| SP | Richards, G.Richards, Garrett >> | 26 | 2014 | R | 72 | 12 | 12 | 6 | 5 | 4.68 | .320 | 1.37 | 8.5 | 3.8 | 7.9 | 73.0 | 69 | 38 | 38 | 11 | 31 | 64 | 0 | 0 | 0 | 0 | 7 | 3 | 5 | 4.60 |
| SP | Foltynewicz, M.Foltynewicz, Michael >> | 26 | 2018 | R | 66 | 12 | 12 | 3 | 6 | 5.28 | .343 | 1.57 | 10.0 | 4.1 | 10.0 | 61.1 | 68 | 37 | 36 | 14 | 28 | 68 | 1 | 0 | 0 | 0 | 3 | 0 | 3 | 5.13 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 100 | 33 | 0 | 5 | 2 | 4.47 | .296 | 1.26 | 8.6 | 2.9 | 12.3 | 44.1 | 42 | 22 | 22 | 8 | 14 | 60 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 3.59 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 87 | 34 | 0 | 0 | 1 | 5.91 | .335 | 1.49 | 9.0 | 4.4 | 9.8 | 35.0 | 35 | 23 | 23 | 11 | 17 | 38 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 6.46 |
| RP | Parker, B.Parker, Blake >> | 32 | 2017 | R | 78 | 29 | 0 | 2 | 2 | 4.89 | .309 | 1.26 | 7.2 | 4.1 | 8.5 | 35.0 | 28 | 19 | 19 | 6 | 16 | 33 | 0 | 5 | 1 | 0 | 0 | 3 | 4 | 4.97 |
| RP | Balfour, G.Balfour, Grant >> | 35 | 2012 | R | 61 | 19 | 0 | 1 | 0 | 2.59 | .291 | 1.23 | 6.4 | 4.9 | 6.4 | 24.1 | 17 | 7 | 7 | 3 | 13 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.83 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 52 | 19 | 0 | 0 | 0 | 3.20 | .224 | 0.87 | 5.8 | 2.2 | 9.7 | 25.1 | 16 | 9 | 9 | 4 | 6 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.64 |
| SP | Romero, R.Romero, Ricky >> | 26 | 2011 | L | 35 | 9 | 0 | 4 | 0 | 3.59 | .312 | 1.34 | 7.7 | 4.5 | 7.9 | 42.2 | 36 | 17 | 17 | 3 | 21 | 37 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.74 |