| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 17 | 17 | 5 | 9 | 3.91 | .314 | 1.38 | 7.7 | 4.8 | 10.3 | 96.2 | 82 | 50 | 42 | 7 | 51 | 110 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 3.25 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 17 | 17 | 7 | 4 | 4.84 | .330 | 1.45 | 10.7 | 2.5 | 6.4 | 109.2 | 129 | 67 | 59 | 12 | 30 | 77 | 3 | 0 | 0 | 0 | 8 | 3 | 0 | 3.93 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 74 | 16 | 16 | 5 | 7 | 6.01 | .355 | 1.64 | 11.8 | 3.0 | 6.0 | 70.1 | 92 | 47 | 47 | 11 | 23 | 47 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.73 |
| SP | Harang, A.Harang, Aaron # >> | 29 | 2007 | R | 52 | 17 | 16 | 5 | 4 | 5.81 | .333 | 1.47 | 10.5 | 2.8 | 7.2 | 93.0 | 108 | 62 | 60 | 13 | 29 | 74 | 1 | 0 | 0 | 0 | 6 | 2 | 2 | 4.23 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 94 | 50 | 0 | 3 | 4 | 4.30 | .335 | 1.47 | 10.2 | 3.1 | 9.9 | 52.1 | 59 | 25 | 25 | 7 | 18 | 57 | 0 | 5 | 0 | 0 | 0 | 2 | 2 | 3.71 |
| RP | Williamson, S.Williamson, Scott >> | 26 | 2002 | R | 52 | 40 | 0 | 0 | 3 | 5.06 | .379 | 1.78 | 9.2 | 7.1 | 10.5 | 42.2 | 43 | 25 | 24 | 4 | 33 | 49 | 0 | 4 | 2 | 0 | 0 | 2 | 4 | 4.40 |
| RP | Donnelly, B.Donnelly, Brendan >> | 32 | 2003 | R | 39 | 33 | 0 | 1 | 2 | 5.77 | .339 | 1.49 | 10.8 | 2.5 | 7.4 | 39.0 | 47 | 28 | 25 | 9 | 11 | 32 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 5.36 |
| RP | Stewart, S.Stewart, Scott >> | 27 | 2002 | L | 28 | 59 | 0 | 4 | 1 | 4.79 | .338 | 1.47 | 9.6 | 3.6 | 8.4 | 47.0 | 50 | 27 | 25 | 4 | 19 | 44 | 0 | 1 | 0 | 0 | 0 | 3 | 3 | 3.64 |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2008 | R | 39 | 24 | 0 | 3 | 0 | 6.00 | .338 | 1.45 | 9.2 | 3.9 | 6.5 | 51.0 | 52 | 36 | 34 | 7 | 22 | 37 | 0 | 3 | 0 | 0 | 0 | 4 | 1 | 4.86 |