| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 5 | 5 | 0 | 4 | 7.96 | .371 | 1.73 | 11.1 | 4.5 | 8.0 | 26.0 | 32 | 24 | 23 | 4 | 13 | 23 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4.85 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 5 | 5 | 2 | 3 | 7.62 | .361 | 1.69 | 12.2 | 3.2 | 6.4 | 28.1 | 38 | 24 | 24 | 9 | 10 | 20 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 6.82 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 5 | 5 | 0 | 4 | 8.67 | .396 | 1.93 | 14.0 | 3.3 | 6.0 | 27.0 | 42 | 31 | 26 | 12 | 10 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.67 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 97 | 11 | 0 | 1 | 0 | 3.86 | .310 | 1.35 | 10.1 | 2.3 | 9.0 | 16.1 | 18 | 7 | 7 | 3 | 4 | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.19 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 13 | 0 | 0 | 1 | 3.18 | .301 | 1.29 | 7.9 | 3.7 | 8.5 | 17.0 | 15 | 6 | 6 | 1 | 7 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.12 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 54 | 9 | 0 | 1 | 0 | 0.71 | .240 | 0.95 | 6.8 | 2.3 | 8.3 | 12.2 | 9 | 1 | 1 | 1 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 42 | 9 | 0 | 0 | 1 | 6.75 | .360 | 1.59 | 9.9 | 5.4 | 14.4 | 10.2 | 11 | 8 | 8 | 2 | 6 | 16 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.50 |
| RP | Manzanillo, J.Manzanillo, Josias >> | 34 | 2001 | R | 30 | 9 | 0 | 0 | 0 | 2.79 | .341 | 1.55 | 11.0 | 4.0 | 11.0 | 9.2 | 11 | 3 | 3 | 0 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.89 |