| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 6 | 6 | 2 | 1 | 2.98 | .270 | 1.04 | 5.8 | 3.6 | 10.1 | 42.1 | 27 | 14 | 14 | 4 | 17 | 47 | 2 | 0 | 0 | 1 | 4 | 3 | 1 | 3.43 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 5 | 5 | 2 | 1 | 4.41 | .324 | 1.44 | 10.1 | 3.1 | 6.8 | 32.2 | 36 | 19 | 16 | 6 | 11 | 24 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 4.97 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 52 | 5 | 5 | 3 | 0 | 4.15 | .333 | 1.50 | 9.8 | 4.0 | 7.4 | 34.2 | 37 | 17 | 16 | 6 | 15 | 28 | 0 | 0 | 0 | 0 | 4 | 0 | 3 | 4.97 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 12 | 0 | 0 | 1 | 3.12 | .257 | 0.98 | 8.5 | 0.5 | 10.1 | 17.1 | 16 | 6 | 6 | 2 | 1 | 19 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.65 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 84 | 12 | 0 | 0 | 2 | 2.30 | .288 | 1.15 | 5.4 | 5.4 | 6.6 | 15.2 | 9 | 4 | 4 | 1 | 9 | 11 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.40 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 78 | 13 | 0 | 1 | 1 | 0.57 | .266 | 1.09 | 6.6 | 3.6 | 9.6 | 15.2 | 11 | 1 | 1 | 0 | 6 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 2.07 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 52 | 7 | 0 | 0 | 1 | 3.00 | .308 | 1.33 | 7.5 | 4.5 | 10.5 | 6.0 | 5 | 2 | 2 | 1 | 3 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.33 |