| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 30 | 30 | 8 | 13 | 4.49 | .312 | 1.33 | 9.0 | 2.9 | 10.1 | 184.1 | 185 | 95 | 92 | 23 | 60 | 207 | 5 | 0 | 0 | 2 | 16 | 6 | 5 | 3.45 |
| SP | Duchscherer, J.Duchscherer, Justin † >> | 31 | 2008 | R | 86 | 29 | 29 | 14 | 9 | 4.02 | .318 | 1.39 | 9.3 | 3.2 | 6.0 | 186.0 | 192 | 95 | 83 | 22 | 66 | 124 | 0 | 0 | 0 | 0 | 18 | 2 | 2 | 4.30 |
| SP | Zito, B.Zito, Barry † # >> | 24 | 2002 | L | 65 | 29 | 29 | 18 | 6 | 3.13 | .280 | 1.14 | 7.0 | 3.3 | 6.0 | 195.1 | 151 | 69 | 68 | 17 | 72 | 130 | 2 | 0 | 0 | 1 | 20 | 5 | 3 | 3.98 |
| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 81 | 29 | 29 | 14 | 7 | 5.05 | .363 | 1.66 | 11.3 | 3.7 | 9.9 | 162.1 | 204 | 91 | 91 | 20 | 66 | 178 | 0 | 0 | 0 | 0 | 8 | 7 | 4 | 3.76 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 89 | 0 | 7 | 1 | 3.43 | .295 | 1.24 | 6.3 | 4.8 | 8.7 | 97.0 | 68 | 39 | 37 | 4 | 52 | 94 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 3.27 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 73 | 0 | 4 | 1 | 2.75 | .262 | 1.03 | 6.8 | 2.6 | 8.3 | 68.2 | 51 | 21 | 21 | 7 | 20 | 63 | 0 | 8 | 3 | 0 | 0 | 2 | 2 | 3.46 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 65 | 70 | 0 | 3 | 1 | 4.91 | .293 | 1.23 | 8.1 | 3.1 | 9.0 | 58.2 | 52 | 33 | 32 | 10 | 20 | 58 | 0 | 11 | 0 | 0 | 0 | 1 | 5 | 4.33 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 69 | 67 | 0 | 3 | 6 | 4.64 | .347 | 1.55 | 8.6 | 5.3 | 7.9 | 64.0 | 61 | 35 | 33 | 11 | 38 | 56 | 0 | 6 | 4 | 0 | 0 | 3 | 2 | 5.41 |