| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 92 | 11 | 11 | 7 | 3 | 2.33 | .264 | 1.04 | 6.8 | 2.6 | 9.6 | 81.0 | 61 | 21 | 21 | 7 | 23 | 86 | 1 | 0 | 0 | 0 | 8 | 3 | 1 | 2.96 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 84 | 11 | 11 | 5 | 5 | 3.48 | .272 | 1.12 | 7.9 | 2.3 | 7.1 | 72.1 | 63 | 29 | 28 | 7 | 18 | 57 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 3.43 |
| SP | Richards, G.Richards, Garrett >> | 26 | 2014 | R | 75 | 10 | 10 | 2 | 5 | 6.11 | .368 | 1.71 | 10.4 | 5.0 | 7.7 | 56.0 | 65 | 38 | 38 | 4 | 31 | 48 | 0 | 0 | 0 | 0 | 4 | 2 | 9 | 3.98 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 69 | 10 | 10 | 3 | 3 | 5.22 | .351 | 1.62 | 11.6 | 3.2 | 9.2 | 60.1 | 77 | 35 | 35 | 10 | 21 | 61 | 0 | 0 | 0 | 0 | 5 | 0 | 2 | 4.18 |
| SP | Syndergaard, N.Syndergaard, Noah >> | 22 | 2015 | R | 59 | 10 | 10 | 3 | 3 | 4.70 | .296 | 1.23 | 8.7 | 2.4 | 10.7 | 59.1 | 57 | 32 | 31 | 13 | 16 | 70 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 4.41 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 22 | 0 | 1 | 3 | 4.15 | .376 | 1.81 | 11.1 | 5.2 | 10.0 | 26.0 | 32 | 12 | 12 | 2 | 15 | 29 | 0 | 4 | 2 | 0 | 0 | 0 | 1 | 3.50 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 88 | 28 | 0 | 1 | 2 | 3.73 | .282 | 1.15 | 5.5 | 4.9 | 8.7 | 31.1 | 19 | 14 | 13 | 5 | 17 | 30 | 0 | 5 | 2 | 0 | 0 | 1 | 2 | 4.90 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 21 | 0 | 1 | 1 | 3.24 | .279 | 1.12 | 6.8 | 3.2 | 11.5 | 25.0 | 19 | 9 | 9 | 2 | 9 | 32 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 2.68 |
| RP | Balfour, G.Balfour, Grant >> | 35 | 2012 | R | 62 | 20 | 0 | 0 | 0 | 5.03 | .253 | 1.02 | 6.6 | 2.8 | 8.5 | 19.2 | 14 | 12 | 11 | 3 | 6 | 18 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.11 |
| RP | Janssen, C.Janssen, Casey >> | 31 | 2012 | R | 55 | 12 | 0 | 0 | 2 | 7.98 | .389 | 1.91 | 12.9 | 5.1 | 9.6 | 14.2 | 20 | 13 | 13 | 4 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.29 |