| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 96 | 22 | 22 | 9 | 9 | 4.69 | .332 | 1.46 | 10.1 | 3.1 | 10.1 | 136.1 | 152 | 71 | 71 | 17 | 47 | 153 | 2 | 0 | 0 | 1 | 12 | 4 | 2 | 3.50 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 83 | 22 | 22 | 7 | 7 | 4.46 | .310 | 1.32 | 9.9 | 1.9 | 7.3 | 135.1 | 149 | 67 | 67 | 20 | 29 | 109 | 0 | 0 | 0 | 0 | 10 | 4 | 5 | 4.04 |
| SP | Clevinger, M.Clevinger, Mike >> | 28 | 2019 | R | 74 | 21 | 21 | 7 | 6 | 5.35 | .343 | 1.53 | 10.7 | 3.1 | 9.4 | 109.1 | 130 | 70 | 65 | 17 | 37 | 114 | 0 | 0 | 0 | 0 | 9 | 4 | 0 | 4.06 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 68 | 21 | 21 | 6 | 11 | 6.25 | .377 | 1.81 | 11.8 | 4.6 | 7.9 | 126.2 | 165 | 89 | 88 | 21 | 64 | 110 | 3 | 0 | 0 | 0 | 7 | 1 | 2 | 4.97 |
| SP | Wainwright, A.Wainwright, Adam † >> | 29 | 2010 | R | 55 | 24 | 19 | 10 | 5 | 4.14 | .321 | 1.40 | 8.8 | 3.8 | 7.3 | 130.1 | 127 | 63 | 60 | 18 | 55 | 106 | 6 | 1 | 0 | 2 | 11 | 3 | 2 | 4.51 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 66 | 0 | 5 | 3 | 3.35 | .294 | 1.25 | 8.7 | 2.7 | 11.3 | 88.2 | 85 | 35 | 33 | 10 | 26 | 110 | 0 | 7 | 3 | 0 | 0 | 0 | 1 | 2.86 |
| RP | Boxberger, B.Boxberger, Brad † >> | 26 | 2014 | R | 87 | 57 | 0 | 4 | 3 | 1.82 | .255 | 1.01 | 5.7 | 3.4 | 9.7 | 79.0 | 50 | 16 | 16 | 5 | 30 | 85 | 0 | 5 | 0 | 0 | 0 | 1 | 2 | 2.85 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 76 | 46 | 0 | 4 | 4 | 3.27 | .292 | 1.22 | 7.7 | 3.3 | 10.5 | 55.0 | 47 | 22 | 20 | 6 | 20 | 64 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 3.24 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 63 | 37 | 0 | 3 | 1 | 3.94 | .318 | 1.35 | 9.8 | 2.4 | 10.5 | 48.0 | 52 | 21 | 21 | 4 | 13 | 56 | 0 | 5 | 0 | 0 | 0 | 2 | 0 | 2.69 |