| SP | Bumgarner, M.Bumgarner, Madison >> | 26 | 2016 | L | 76 | 11 | 11 | 1 | 6 | 8.14 | .381 | 1.83 | 13.3 | 3.4 | 11.4 | 48.2 | 71 | 47 | 44 | 10 | 18 | 61 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.35 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 22 | 0 | 3 | 3 | 4.10 | .307 | 1.33 | 9.3 | 2.8 | 8.7 | 26.1 | 27 | 12 | 12 | 3 | 8 | 25 | 0 | 8 | 2 | 0 | 0 | 0 | 3 | 3.50 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 75 | 32 | 0 | 1 | 2 | 5.35 | .345 | 1.53 | 11.1 | 2.8 | 8.8 | 38.2 | 47 | 25 | 23 | 10 | 12 | 37 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 5.58 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 64 | 26 | 0 | 0 | 4 | 5.93 | .350 | 1.55 | 7.8 | 6.3 | 11.4 | 30.1 | 26 | 20 | 20 | 6 | 21 | 38 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 5.37 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 34 | 2014 | R | 48 | 23 | 0 | 0 | 1 | 2.84 | .269 | 1.03 | 6.8 | 2.5 | 6.5 | 25.1 | 19 | 8 | 8 | 1 | 7 | 18 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.16 |
| RP | Soriano, R.Soriano, Rafael >> | 31 | 2010 | R | 80 | 16 | 0 | 1 | 1 | 4.42 | .360 | 1.69 | 10.0 | 5.5 | 11.5 | 18.1 | 20 | 9 | 9 | 2 | 11 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.72 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 66 | 12 | 0 | 1 | 1 | 5.65 | .295 | 1.19 | 7.7 | 3.2 | 6.4 | 14.1 | 12 | 9 | 9 | 4 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.57 |