| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 15 | 15 | 6 | 7 | 3.55 | .271 | 1.09 | 7.4 | 2.4 | 9.7 | 114.0 | 94 | 50 | 45 | 13 | 30 | 123 | 4 | 0 | 0 | 2 | 9 | 3 | 2 | 3.19 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 15 | 15 | 5 | 4 | 3.66 | .325 | 1.43 | 9.2 | 3.8 | 8.0 | 103.1 | 105 | 43 | 42 | 5 | 43 | 92 | 1 | 0 | 0 | 1 | 11 | 1 | 1 | 3.13 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 15 | 15 | 6 | 5 | 4.53 | .320 | 1.41 | 10.2 | 2.5 | 4.1 | 109.1 | 124 | 56 | 55 | 15 | 30 | 50 | 3 | 0 | 0 | 1 | 6 | 0 | 1 | 4.70 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 15 | 15 | 5 | 6 | 4.77 | .320 | 1.40 | 9.8 | 2.9 | 7.3 | 94.1 | 102 | 55 | 50 | 15 | 30 | 76 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 4.45 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 14 | 14 | 7 | 7 | 4.99 | .310 | 1.33 | 9.0 | 3.0 | 5.4 | 106.1 | 106 | 65 | 59 | 11 | 35 | 64 | 7 | 0 | 0 | 0 | 5 | 2 | 3 | 4.19 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 26 | 0 | 2 | 2 | 3.03 | .305 | 1.29 | 7.0 | 4.8 | 8.4 | 32.2 | 25 | 11 | 11 | 3 | 17 | 30 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 4.03 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 21 | 0 | 2 | 2 | 4.13 | .273 | 1.13 | 6.4 | 3.8 | 11.3 | 24.0 | 17 | 11 | 11 | 2 | 10 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 6 | 0 | 0 | 0 | 8.10 | .394 | 1.95 | 12.0 | 7.5 | 7.5 | 6.2 | 8 | 6 | 6 | 1 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 11 | 0 | 2 | 0 | 1.80 | .268 | 1.10 | 7.2 | 2.7 | 9.9 | 10.0 | 8 | 2 | 2 | 2 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.30 |