| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 29 | 29 | 9 | 15 | 4.22 | .326 | 1.44 | 9.4 | 3.7 | 7.9 | 202.2 | 210 | 98 | 95 | 24 | 82 | 177 | 7 | 0 | 0 | 0 | 14 | 2 | 9 | 4.04 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 29 | 29 | 7 | 12 | 5.38 | .324 | 1.41 | 9.6 | 3.1 | 8.6 | 170.2 | 182 | 103 | 102 | 28 | 58 | 163 | 2 | 0 | 0 | 0 | 13 | 5 | 9 | 4.34 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 27 | 9 | 11 | 4.82 | .315 | 1.38 | 9.7 | 2.7 | 5.2 | 173.2 | 187 | 102 | 93 | 21 | 52 | 99 | 5 | 0 | 0 | 1 | 14 | 1 | 2 | 4.35 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 81 | 0 | 2 | 1 | 3.08 | .294 | 1.22 | 7.1 | 3.9 | 8.6 | 102.1 | 81 | 37 | 35 | 11 | 44 | 97 | 0 | 9 | 1 | 0 | 0 | 3 | 7 | 3.88 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 71 | 0 | 4 | 2 | 3.10 | .274 | 1.10 | 5.9 | 4.1 | 5.5 | 101.2 | 66 | 39 | 35 | 10 | 46 | 62 | 0 | 3 | 2 | 0 | 0 | 3 | 0 | 4.51 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 62 | 0 | 4 | 2 | 4.48 | .317 | 1.34 | 8.2 | 3.9 | 7.7 | 80.1 | 73 | 41 | 40 | 17 | 35 | 68 | 0 | 8 | 0 | 0 | 0 | 4 | 3 | 5.53 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 46 | 0 | 4 | 3 | 3.26 | .300 | 1.29 | 7.2 | 4.6 | 9.0 | 49.2 | 39 | 19 | 18 | 4 | 25 | 49 | 0 | 2 | 2 | 0 | 0 | 0 | 6 | 3.59 |