| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 23 | 23 | 3 | 8 | 4.16 | .294 | 1.21 | 8.5 | 2.5 | 10.4 | 138.1 | 130 | 74 | 64 | 18 | 38 | 160 | 0 | 0 | 0 | 0 | 13 | 5 | 0 | 3.31 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 21 | 21 | 8 | 10 | 4.67 | .344 | 1.53 | 10.6 | 3.3 | 6.1 | 121.1 | 142 | 74 | 63 | 11 | 44 | 82 | 1 | 0 | 0 | 1 | 12 | 5 | 6 | 4.04 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 22 | 21 | 3 | 11 | 8.24 | .398 | 1.97 | 13.2 | 4.7 | 6.6 | 78.2 | 114 | 80 | 72 | 21 | 41 | 57 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.65 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 22 | 20 | 5 | 12 | 6.97 | .368 | 1.73 | 12.3 | 3.3 | 4.9 | 102.0 | 139 | 88 | 79 | 23 | 37 | 56 | 3 | 0 | 0 | 0 | 5 | 2 | 3 | 5.98 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 79 | 0 | 2 | 6 | 5.30 | .310 | 1.34 | 7.5 | 4.5 | 9.8 | 93.1 | 78 | 61 | 55 | 8 | 47 | 101 | 0 | 3 | 2 | 0 | 0 | 1 | 12 | 3.49 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 71 | 0 | 3 | 4 | 5.90 | .362 | 1.68 | 11.3 | 3.9 | 10.4 | 76.1 | 95 | 55 | 50 | 21 | 33 | 88 | 0 | 7 | 2 | 0 | 0 | 2 | 6 | 5.66 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 62 | 0 | 1 | 10 | 5.54 | .343 | 1.55 | 9.3 | 4.6 | 9.8 | 78.0 | 81 | 59 | 48 | 10 | 40 | 85 | 0 | 2 | 4 | 0 | 0 | 1 | 1 | 4.06 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 55 | 0 | 2 | 1 | 4.76 | .315 | 1.34 | 8.5 | 3.6 | 9.3 | 68.0 | 64 | 38 | 36 | 7 | 27 | 70 | 0 | 3 | 1 | 0 | 0 | 3 | 2 | 3.60 |