| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 29 | 29 | 16 | 9 | 3.81 | .281 | 1.13 | 8.3 | 1.9 | 8.6 | 210.1 | 193 | 93 | 89 | 21 | 45 | 200 | 3 | 0 | 0 | 0 | 16 | 8 | 5 | 3.15 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 28 | 28 | 12 | 7 | 3.90 | .306 | 1.31 | 9.1 | 2.7 | 5.3 | 191.1 | 194 | 99 | 83 | 20 | 57 | 112 | 6 | 0 | 0 | 2 | 14 | 2 | 3 | 4.12 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 27 | 27 | 12 | 12 | 3.99 | .301 | 1.27 | 8.7 | 2.7 | 5.8 | 196.0 | 190 | 95 | 87 | 20 | 58 | 126 | 8 | 0 | 0 | 1 | 17 | 5 | 2 | 4.01 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 27 | 27 | 11 | 7 | 5.20 | .322 | 1.39 | 10.3 | 2.3 | 9.4 | 150.2 | 171 | 92 | 87 | 21 | 39 | 157 | 3 | 0 | 0 | 1 | 11 | 5 | 2 | 3.61 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 77 | 0 | 3 | 2 | 3.29 | .297 | 1.22 | 7.3 | 3.7 | 9.6 | 63.0 | 51 | 25 | 23 | 7 | 26 | 67 | 0 | 7 | 1 | 0 | 0 | 3 | 3 | 3.70 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 53 | 0 | 3 | 2 | 3.38 | .263 | 1.07 | 6.3 | 3.4 | 6.3 | 53.1 | 37 | 26 | 20 | 5 | 20 | 37 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 3.96 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 30 | 0 | 4 | 4 | 4.50 | .294 | 1.19 | 6.2 | 4.5 | 6.8 | 32.0 | 22 | 17 | 16 | 5 | 16 | 24 | 0 | 3 | 4 | 0 | 0 | 2 | 0 | 5.22 |
| RP | Hiller, J.Hiller, John >> | 30 | 1973 | L | 25 | 20 | 0 | 1 | 0 | 4.30 | .313 | 1.36 | 7.7 | 5.1 | 7.1 | 14.2 | 12 | 8 | 7 | 1 | 8 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.07 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 23 | 0 | 0 | 4 | 4.50 | .291 | 1.23 | 9.7 | 1.4 | 8.3 | 26.0 | 28 | 13 | 13 | 7 | 4 | 24 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.12 |