| SP | Guidry, R.Guidry, Ron † >> | 28 | 1978 | L | 91 | 36 | 36 | 21 | 5 | 2.95 | .282 | 1.17 | 8.1 | 2.5 | 6.7 | 262.1 | 235 | 110 | 86 | 29 | 72 | 194 | 14 | 0 | 0 | 7 | 23 | 2 | 4 | 3.81 |
| SP | Cortes Jr., N.Cortes Jr., Nestor >> | 27 | 2022 | L | 98 | 34 | 34 | 13 | 7 | 4.05 | .314 | 1.34 | 9.0 | 3.0 | 8.6 | 188.2 | 189 | 90 | 85 | 19 | 63 | 179 | 0 | 0 | 0 | 0 | 17 | 7 | 4 | 3.53 |
| SP | Severino, L.Severino, Luis >> | 23 | 2017 | R | 68 | 35 | 35 | 12 | 12 | 5.40 | .345 | 1.55 | 10.2 | 3.7 | 8.4 | 188.1 | 213 | 124 | 113 | 36 | 78 | 175 | 0 | 0 | 0 | 0 | 15 | 6 | 4 | 4.97 |
| SP | Mussina, M.Mussina, Mike # >> | 35 | 2003 | R | 58 | 33 | 33 | 9 | 13 | 5.91 | .352 | 1.59 | 11.8 | 2.5 | 5.9 | 172.0 | 226 | 128 | 113 | 27 | 48 | 113 | 0 | 0 | 0 | 0 | 10 | 6 | 3 | 4.67 |
| SP | Hunter, C.Hunter, Catfish >> | 30 | 1976 | R | 52 | 31 | 31 | 6 | 15 | 7.52 | .371 | 1.73 | 12.0 | 3.5 | 5.1 | 142.1 | 190 | 126 | 119 | 25 | 56 | 81 | 2 | 0 | 0 | 1 | 8 | 6 | 3 | 5.46 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 94 | 90 | 0 | 5 | 5 | 3.79 | .278 | 1.14 | 8.2 | 2.0 | 7.6 | 128.1 | 117 | 57 | 54 | 10 | 29 | 108 | 0 | 8 | 6 | 0 | 0 | 2 | 1 | 3.05 |
| RP | Cole, G.Cole, Gerrit # >> | 29 | 2020 | R | 65 | 71 | 0 | 8 | 5 | 5.01 | .336 | 1.50 | 8.7 | 4.9 | 9.6 | 111.1 | 107 | 66 | 62 | 14 | 60 | 119 | 0 | 5 | 2 | 0 | 0 | 2 | 4 | 4.17 |
| RP | Wolfe, B.Wolfe, Barney >> | 28 | 1904 | R | 32 | 40 | 0 | 3 | 0 | 5.54 | .347 | 1.58 | 12.1 | 2.1 | 4.8 | 52.0 | 70 | 33 | 32 | 11 | 12 | 28 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 5.42 |