| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 86 | 18 | 18 | 14 | 2 | 1.98 | .215 | 0.81 | 5.9 | 1.4 | 7.5 | 149.2 | 97 | 34 | 33 | 14 | 24 | 124 | 10 | 0 | 0 | 5 | 15 | 2 | 2 | 3.08 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 97 | 17 | 17 | 0 | 2 | 4.06 | .289 | 1.22 | 8.8 | 2.3 | 5.7 | 44.1 | 43 | 20 | 20 | 4 | 11 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.66 |
| SP | Greinke, Z.Greinke, Zack # >> | 36 | 2019 | R | 72 | 17 | 17 | 9 | 5 | 4.13 | .292 | 1.22 | 9.2 | 1.8 | 6.0 | 113.1 | 115 | 54 | 52 | 15 | 23 | 75 | 2 | 0 | 0 | 1 | 9 | 2 | 3 | 4.06 |
| SP | Kelly, M.Kelly, Merrill † >> | 36 | 2025 | R | 56 | 18 | 17 | 15 | 3 | 2.18 | .259 | 1.02 | 7.1 | 2.1 | 6.5 | 115.2 | 91 | 30 | 28 | 11 | 27 | 83 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.58 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 67 | 44 | 0 | 1 | 1 | 2.61 | .264 | 1.02 | 5.1 | 4.2 | 8.8 | 58.2 | 33 | 17 | 17 | 4 | 27 | 57 | 0 | 3 | 1 | 0 | 0 | 3 | 3 | 3.48 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 66 | 42 | 0 | 4 | 2 | 3.26 | .270 | 1.11 | 5.9 | 4.2 | 8.1 | 49.2 | 32 | 18 | 18 | 7 | 23 | 44 | 0 | 7 | 4 | 0 | 0 | 0 | 2 | 4.47 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 52 | 18 | 0 | 3 | 1 | 4.74 | .296 | 1.26 | 6.6 | 4.7 | 6.6 | 19.0 | 14 | 10 | 10 | 2 | 10 | 14 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 4.47 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 51 | 18 | 0 | 0 | 0 | 0.50 | .250 | 1.00 | 4.5 | 4.5 | 5.5 | 18.0 | 9 | 1 | 1 | 0 | 9 | 11 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Crichton, S.Crichton, Stefan >> | 27 | 2019 | R | 43 | 15 | 0 | 0 | 0 | 2.37 | .269 | 1.05 | 6.2 | 3.3 | 10.4 | 19.0 | 13 | 5 | 5 | 4 | 7 | 22 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.68 |
| SP | Gilbert, T.Gilbert, Tyler >> | 27 | 2021 | L | 60 | 20 | 0 | 7 | 2 | 3.70 | .315 | 1.34 | 7.3 | 4.9 | 5.8 | 48.2 | 39 | 20 | 20 | 7 | 26 | 31 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.35 |