| SP | George, B.George, Bill >> | 23 | 1888 | L | 93 | 17 | 17 | 0 | 1 | 4.03 | .307 | 1.33 | 7.8 | 4.2 | 6.4 | 58.0 | 50 | 26 | 26 | 3 | 27 | 41 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 3.66 |
| CL | Romo, S.Romo, Sergio † >> | 25 | 2008 | R | 90 | 51 | 0 | 4 | 4 | 4.26 | .302 | 1.26 | 6.5 | 4.9 | 6.8 | 57.0 | 41 | 31 | 27 | 8 | 31 | 43 | 0 | 22 | 3 | 0 | 0 | 2 | 0 | 5.05 |
| SU | Lopez, J.Lopez, Javier >> | 38 | 2015 | L | 71 | 48 | 0 | 4 | 1 | 4.22 | .358 | 1.63 | 10.1 | 4.7 | 5.8 | 59.2 | 66 | 31 | 28 | 4 | 31 | 38 | 0 | 1 | 3 | 0 | 0 | 3 | 0 | 4.32 |
| RP | Moronta, R.Moronta, Reyes # >> | 25 | 2018 | R | 54 | 51 | 0 | 9 | 3 | 3.84 | .326 | 1.45 | 8.5 | 4.7 | 7.8 | 58.2 | 55 | 26 | 25 | 5 | 30 | 50 | 0 | 0 | 4 | 0 | 0 | 0 | 3 | 3.95 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 78 | 50 | 0 | 6 | 0 | 3.21 | .275 | 1.10 | 6.6 | 3.4 | 8.9 | 61.2 | 45 | 27 | 22 | 7 | 23 | 60 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 3.75 |