| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 100 | 34 | 34 | 1 | 7 | 3.93 | .284 | 1.17 | 7.7 | 2.9 | 5.6 | 94.0 | 80 | 41 | 41 | 11 | 30 | 58 | 0 | 0 | 0 | 0 | 1 | 2 | 3 | 4.31 |
| SP | Johnson, R.Johnson, Randy † # >> | 41 | 2004 | L | 89 | 32 | 32 | 18 | 7 | 2.45 | .234 | 0.90 | 6.5 | 1.7 | 8.2 | 260.1 | 187 | 76 | 71 | 23 | 48 | 238 | 9 | 0 | 0 | 4 | 24 | 3 | 3 | 2.91 |
| SP | Greinke, Z.Greinke, Zack >> | 36 | 2019 | R | 78 | 31 | 18 | 12 | 5 | 3.37 | .295 | 1.23 | 8.3 | 2.8 | 6.2 | 152.1 | 140 | 60 | 57 | 16 | 47 | 104 | 0 | 0 | 0 | 0 | 9 | 4 | 3 | 4.01 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 75 | 84 | 0 | 8 | 7 | 3.15 | .255 | 1.00 | 6.2 | 2.8 | 6.0 | 117.0 | 80 | 43 | 41 | 12 | 37 | 78 | 0 | 5 | 4 | 0 | 0 | 3 | 7 | 4.03 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 70 | 83 | 0 | 3 | 4 | 3.63 | .290 | 1.20 | 5.4 | 5.4 | 8.2 | 106.2 | 64 | 44 | 43 | 9 | 64 | 96 | 0 | 10 | 6 | 0 | 0 | 3 | 6 | 4.19 |
| RP | Núnez, D.Núnez, Dedniel >> | 28 | 2024 | R | 65 | 59 | 0 | 6 | 5 | 2.71 | .227 | 0.85 | 5.2 | 2.5 | 8.3 | 79.2 | 46 | 27 | 24 | 8 | 22 | 73 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 3.38 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 55 | 26 | 0 | 1 | 4 | 3.94 | .294 | 1.19 | 7.0 | 3.7 | 8.4 | 32.0 | 25 | 14 | 14 | 2 | 13 | 30 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 3.34 |
| RP | Curtiss, J.Curtiss, John >> | 32 | 2025 | R | 40 | 22 | 0 | 1 | 1 | 4.50 | .323 | 1.39 | 8.4 | 4.2 | 5.1 | 28.0 | 26 | 18 | 14 | 6 | 13 | 16 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 6.14 |
| RP | Medders, B.Medders, Brandon >> | 25 | 2005 | R | 39 | 27 | 0 | 1 | 1 | 2.93 | .287 | 1.21 | 7.8 | 3.3 | 9.0 | 30.2 | 26 | 10 | 10 | 1 | 11 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.53 |
| SP | Kelly, M.Kelly, Merrill >> | 31 | 2020 | R | 70 | 25 | 13 | 2 | 3 | 5.28 | .308 | 1.32 | 10.5 | 1.5 | 6.3 | 61.1 | 71 | 36 | 36 | 11 | 10 | 43 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.48 |
| SP | McGough, S.McGough, Scott >> | 33 | 2023 | R | 46 | 28 | 13 | 4 | 3 | 4.03 | .363 | 1.68 | 9.7 | 5.4 | 7.3 | 38.0 | 41 | 18 | 17 | 3 | 23 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.29 |