| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 20 | 20 | 9 | 6 | 3.47 | .267 | 1.08 | 7.8 | 2.0 | 9.1 | 124.2 | 108 | 50 | 48 | 16 | 27 | 125 | 1 | 0 | 0 | 0 | 14 | 1 | 0 | 3.34 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 20 | 19 | 9 | 8 | 4.79 | .302 | 1.26 | 8.8 | 2.5 | 4.5 | 107.0 | 105 | 63 | 57 | 15 | 30 | 53 | 2 | 0 | 0 | 0 | 10 | 4 | 0 | 4.79 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 48 | 0 | 5 | 4 | 3.44 | .276 | 1.13 | 7.1 | 3.1 | 8.8 | 52.1 | 41 | 20 | 20 | 5 | 18 | 51 | 0 | 15 | 3 | 0 | 0 | 1 | 0 | 3.38 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 51 | 0 | 1 | 2 | 4.33 | .328 | 1.41 | 7.5 | 5.2 | 8.3 | 54.0 | 45 | 27 | 26 | 9 | 31 | 50 | 0 | 0 | 4 | 0 | 0 | 3 | 2 | 5.20 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 41 | 0 | 1 | 0 | 6.51 | .316 | 1.38 | 8.8 | 3.6 | 7.3 | 47.0 | 46 | 34 | 34 | 6 | 19 | 38 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.26 |