| SP | Maddux, G.Maddux, Greg $$ >> | 29 | 1995 | R | 89 | 11 | 11 | 4 | 5 | 5.08 | .321 | 1.40 | 10.9 | 1.9 | 4.0 | 72.2 | 87 | 43 | 41 | 12 | 15 | 32 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.94 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 11 | 11 | 4 | 2 | 4.61 | .343 | 1.54 | 10.6 | 3.3 | 5.4 | 68.1 | 80 | 36 | 35 | 6 | 25 | 41 | 1 | 0 | 0 | 0 | 5 | 2 | 2 | 4.13 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 11 | 11 | 5 | 3 | 4.88 | .331 | 1.47 | 9.3 | 4.1 | 5.5 | 62.2 | 64 | 36 | 34 | 7 | 28 | 38 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 4.65 |
| RP | Kuo, H.Kuo, Hong-Chih $ >> | 29 | 2010 | L | 90 | 31 | 0 | 1 | 0 | 0.99 | .281 | 1.13 | 6.3 | 4.0 | 9.0 | 27.1 | 19 | 3 | 3 | 1 | 12 | 27 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.93 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 29 | 0 | 1 | 0 | 4.18 | .302 | 1.24 | 8.2 | 3.1 | 8.2 | 32.1 | 29 | 17 | 15 | 3 | 11 | 29 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.63 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 23 | 0 | 1 | 1 | 3.63 | .316 | 1.39 | 8.2 | 4.5 | 9.0 | 22.1 | 20 | 10 | 9 | 4 | 11 | 22 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.86 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 15 | 0 | 3 | 0 | 4.60 | .309 | 1.34 | 9.6 | 3.0 | 7.2 | 15.2 | 16 | 8 | 8 | 2 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.13 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 14 | 0 | 1 | 0 | 5.65 | .218 | 0.84 | 5.1 | 2.6 | 9.0 | 14.1 | 8 | 9 | 9 | 4 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.57 |
| SU | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 22 | 0 | 0 | 1 | 1.80 | .265 | 1.08 | 5.8 | 4.0 | 11.9 | 25.0 | 16 | 5 | 5 | 0 | 11 | 33 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 1.68 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 24 | 0 | 2 | 4 | 3.80 | .297 | 1.23 | 9.0 | 2.3 | 7.4 | 23.2 | 23 | 11 | 10 | 2 | 6 | 19 | 0 | 14 | 2 | 0 | 0 | 1 | 0 | 3.39 |