| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 92 | 13 | 13 | 4 | 6 | 4.08 | .292 | 1.18 | 8.6 | 2.1 | 7.5 | 90.1 | 86 | 42 | 41 | 14 | 21 | 75 | 2 | 0 | 0 | 1 | 7 | 5 | 0 | 4.22 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 79 | 12 | 12 | 4 | 5 | 6.07 | .357 | 1.64 | 9.5 | 5.3 | 9.9 | 69.2 | 73 | 49 | 47 | 15 | 41 | 76 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 5.49 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 68 | 12 | 12 | 1 | 6 | 8.48 | .381 | 1.83 | 13.6 | 3.0 | 8.5 | 57.1 | 86 | 56 | 54 | 20 | 19 | 54 | 1 | 0 | 0 | 0 | 3 | 1 | 1 | 6.72 |
| SP | Wainwright, A.Wainwright, Adam # >> | 29 | 2010 | R | 55 | 12 | 12 | 2 | 4 | 5.68 | .354 | 1.61 | 11.5 | 3.0 | 7.9 | 76.0 | 97 | 49 | 48 | 15 | 25 | 67 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 4.91 |
| RP | Petit, Y.Petit, Yusmeiro >> | 35 | 2019 | R | 70 | 30 | 0 | 1 | 1 | 3.11 | .289 | 1.19 | 8.8 | 2.2 | 7.1 | 37.2 | 36 | 14 | 13 | 3 | 9 | 29 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.30 |
| RP | Knebel, C.Knebel, Corey >> | 25 | 2017 | R | 32 | 21 | 0 | 2 | 0 | 5.24 | .362 | 1.66 | 8.2 | 7.0 | 13.9 | 22.1 | 20 | 19 | 13 | 5 | 17 | 34 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.32 |
| SP | Burnett, A.Burnett, A.J. >> | 36 | 2013 | R | 20 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Paxton, J.Paxton, James >> | 29 | 2018 | L | 45 | 14 | 0 | 2 | 2 | 6.69 | .379 | 1.69 | 12.6 | 2.6 | 10.0 | 35.0 | 49 | 26 | 26 | 8 | 10 | 39 | 0 | 2 | 0 | 0 | 0 | 5 | 0 | 5.03 |