| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 13 | 13 | 5 | 4 | 4.74 | .327 | 1.42 | 9.6 | 3.3 | 9.5 | 79.2 | 84 | 45 | 42 | 15 | 29 | 83 | 1 | 0 | 0 | 0 | 7 | 3 | 2 | 4.58 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 82 | 13 | 13 | 9 | 1 | 4.25 | .268 | 1.07 | 7.3 | 2.5 | 8.3 | 84.2 | 68 | 40 | 40 | 12 | 23 | 77 | 3 | 0 | 0 | 0 | 6 | 2 | 1 | 3.92 |
| SP | Giolito, L.Giolito, Lucas >> | 24 | 2019 | R | 71 | 13 | 13 | 2 | 5 | 6.91 | .394 | 1.94 | 12.5 | 5.1 | 9.3 | 57.1 | 79 | 46 | 44 | 10 | 32 | 59 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 4.95 |
| SP | Foltynewicz, M.Foltynewicz, Michael >> | 26 | 2018 | R | 66 | 12 | 12 | 2 | 6 | 8.19 | .393 | 1.88 | 12.6 | 4.5 | 9.8 | 48.1 | 67 | 45 | 44 | 11 | 24 | 52 | 0 | 0 | 0 | 0 | 2 | 3 | 2 | 5.50 |
| SP | Bauer, T.Bauer, Trevor >> | 27 | 2018 | R | 60 | 12 | 12 | 6 | 4 | 5.15 | .347 | 1.56 | 9.4 | 4.8 | 9.7 | 64.2 | 67 | 41 | 37 | 11 | 34 | 69 | 0 | 0 | 0 | 0 | 8 | 2 | 6 | 4.77 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 81 | 30 | 0 | 3 | 0 | 4.17 | .337 | 1.50 | 9.0 | 4.8 | 12.5 | 36.2 | 36 | 17 | 17 | 5 | 19 | 50 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.69 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 31 | 0 | 3 | 2 | 5.25 | .329 | 1.44 | 9.5 | 3.5 | 10.8 | 36.0 | 38 | 21 | 21 | 3 | 14 | 43 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 2.94 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 63 | 18 | 0 | 4 | 0 | 3.63 | .272 | 0.99 | 6.5 | 2.5 | 11.0 | 22.1 | 16 | 9 | 9 | 2 | 6 | 27 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 2.95 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 31 | 0 | 2 | 2 | 2.76 | .234 | 0.92 | 6.8 | 1.7 | 10.1 | 32.2 | 24 | 10 | 10 | 2 | 6 | 36 | 0 | 18 | 2 | 0 | 0 | 0 | 0 | 2.13 |