| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 7 | 7 | 4 | 2 | 3.00 | .318 | 1.40 | 9.6 | 3.0 | 5.6 | 48.0 | 51 | 16 | 16 | 1 | 16 | 30 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 3.02 |
| SP | Steele, E.Steele, Elmer >> | 22 | 1908 | R | 78 | 7 | 7 | 3 | 1 | 3.84 | .299 | 1.28 | 9.5 | 2.2 | 5.4 | 58.2 | 61 | 26 | 25 | 8 | 14 | 35 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 4.31 |
| SP | Martinez, P.Martinez, Pedro >> | 30 | 2001 | R | 82 | 7 | 7 | 4 | 2 | 2.68 | .312 | 1.34 | 9.4 | 2.7 | 10.1 | 47.0 | 49 | 15 | 14 | 4 | 14 | 53 | 1 | 0 | 0 | 0 | 6 | 1 | 1 | 2.81 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 98 | 20 | 0 | 1 | 0 | 0.42 | .235 | 0.92 | 4.7 | 3.9 | 8.1 | 21.2 | 11 | 5 | 1 | 0 | 9 | 19 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.48 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 94 | 18 | 0 | 1 | 1 | 4.41 | .258 | 1.04 | 8.4 | 1.1 | 8.4 | 16.1 | 15 | 8 | 8 | 1 | 2 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.31 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 86 | 11 | 0 | 2 | 0 | 1.74 | .311 | 1.35 | 5.4 | 7.2 | 5.4 | 10.1 | 6 | 2 | 2 | 0 | 8 | 6 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 76 | 11 | 0 | 1 | 0 | 0.00 | .167 | 0.60 | 4.5 | 1.1 | 7.9 | 8.1 | 4 | 0 | 0 | 0 | 1 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1.63 |
| RP | Uehara, K.Uehara, Koji >> | 41 | 2016 | R | 48 | 6 | 0 | 0 | 0 | 4.70 | .395 | 1.96 | 15.4 | 3.9 | 7.7 | 7.2 | 12 | 4 | 4 | 2 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.29 |