| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 80 | 33 | 33 | 15 | 12 | 3.94 | .314 | 1.33 | 8.4 | 3.7 | 7.3 | 196.1 | 182 | 88 | 86 | 17 | 80 | 160 | 1 | 0 | 0 | 1 | 16 | 7 | 4 | 3.83 |
| SP | Darvish, Y.Darvish, Yu † >> | 35 | 2022 | R | 81 | 31 | 31 | 18 | 8 | 3.00 | .282 | 1.17 | 8.1 | 2.4 | 7.4 | 206.2 | 186 | 70 | 69 | 23 | 55 | 169 | 2 | 0 | 0 | 1 | 23 | 2 | 1 | 3.64 |
| SP | Paddack, C.Paddack, Chris >> | 23 | 2019 | R | 74 | 31 | 31 | 7 | 13 | 3.60 | .307 | 1.29 | 8.6 | 3.1 | 8.3 | 165.0 | 157 | 66 | 66 | 14 | 56 | 153 | 0 | 0 | 0 | 0 | 13 | 6 | 2 | 3.38 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 73 | 31 | 31 | 16 | 6 | 3.51 | .277 | 1.15 | 6.7 | 3.7 | 7.4 | 197.1 | 147 | 77 | 77 | 17 | 80 | 162 | 0 | 0 | 0 | 0 | 20 | 0 | 7 | 3.70 |
| SP | Young, C.Young, Chris † >> | 28 | 2007 | R | 65 | 31 | 30 | 19 | 8 | 2.42 | .264 | 1.06 | 6.2 | 3.4 | 5.6 | 186.1 | 128 | 51 | 50 | 13 | 70 | 115 | 1 | 0 | 0 | 1 | 23 | 2 | 4 | 3.83 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 99 | 68 | 0 | 4 | 3 | 1.88 | .237 | 0.90 | 4.4 | 3.8 | 7.8 | 72.0 | 35 | 16 | 15 | 3 | 30 | 62 | 0 | 44 | 3 | 0 | 0 | 2 | 1 | 3.15 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 93 | 78 | 0 | 3 | 3 | 3.56 | .315 | 1.35 | 6.7 | 5.5 | 9.1 | 73.1 | 54 | 29 | 29 | 5 | 45 | 74 | 0 | 2 | 1 | 0 | 0 | 2 | 2 | 3.79 |
| RP | Meredith, C.Meredith, Cla >> | 23 | 2006 | R | 85 | 61 | 0 | 3 | 0 | 3.07 | .295 | 1.24 | 9.5 | 1.8 | 6.5 | 55.2 | 58 | 20 | 19 | 4 | 11 | 40 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.15 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 78 | 95 | 0 | 4 | 2 | 4.12 | .286 | 1.15 | 8.1 | 2.3 | 8.9 | 63.1 | 57 | 30 | 29 | 7 | 16 | 62 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 3.38 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 77 | 52 | 0 | 3 | 2 | 2.43 | .287 | 1.18 | 7.2 | 3.6 | 10.4 | 40.2 | 32 | 11 | 11 | 3 | 16 | 46 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 2.95 |
| RP | Martinez, P.Martinez, Pedro >> | 25 | 1993 | L | 62 | 41 | 0 | 1 | 1 | 1.60 | .258 | 1.00 | 5.8 | 3.2 | 7.0 | 45.0 | 29 | 9 | 8 | 1 | 16 | 35 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 2.93 |