| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 98 | 30 | 30 | 15 | 8 | 3.52 | .287 | 1.17 | 7.1 | 3.4 | 10.4 | 204.2 | 162 | 81 | 80 | 23 | 77 | 236 | 1 | 0 | 0 | 1 | 21 | 8 | 2 | 3.40 |
| SP | Severino, L.Severino, Luis >> | 23 | 2017 | R | 75 | 29 | 29 | 15 | 7 | 4.46 | .301 | 1.25 | 8.2 | 3.1 | 10.5 | 187.2 | 170 | 96 | 93 | 27 | 64 | 218 | 0 | 0 | 0 | 0 | 17 | 9 | 2 | 3.72 |
| SP | Castillo, L.Castillo, Luis >> | 26 | 2019 | R | 49 | 28 | 28 | 7 | 9 | 5.92 | .357 | 1.64 | 9.4 | 5.4 | 9.3 | 149.0 | 156 | 102 | 98 | 24 | 89 | 154 | 0 | 0 | 0 | 0 | 8 | 3 | 8 | 4.88 |
| SP | Lackey, J.Lackey, John >> | 38 | 2016 | R | 61 | 28 | 27 | 11 | 11 | 5.01 | .321 | 1.39 | 9.6 | 2.9 | 7.1 | 172.1 | 184 | 98 | 96 | 26 | 55 | 136 | 0 | 0 | 0 | 0 | 12 | 5 | 7 | 4.43 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 100 | 79 | 0 | 7 | 5 | 2.93 | .264 | 1.05 | 6.5 | 2.9 | 9.9 | 101.1 | 73 | 33 | 33 | 14 | 33 | 111 | 0 | 13 | 8 | 0 | 0 | 3 | 6 | 3.67 |
| RP | Wagner, B.Wagner, Billy † >> | 39 | 2010 | L | 80 | 58 | 0 | 6 | 1 | 3.41 | .288 | 1.17 | 6.9 | 3.7 | 10.6 | 63.1 | 48 | 24 | 24 | 9 | 26 | 74 | 0 | 12 | 2 | 0 | 0 | 3 | 3 | 3.89 |
| RP | Hochevar, L.Hochevar, Luke # >> | 30 | 2013 | R | 77 | 43 | 0 | 4 | 5 | 4.20 | .274 | 1.09 | 6.6 | 3.2 | 10.8 | 45.0 | 33 | 23 | 21 | 6 | 16 | 54 | 0 | 8 | 5 | 0 | 0 | 2 | 2 | 3.53 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 30 | 0 | 4 | 0 | 2.30 | .234 | 0.88 | 6.0 | 2.0 | 8.7 | 27.1 | 18 | 7 | 7 | 3 | 6 | 26 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.30 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 45 | 16 | 0 | 2 | 1 | 4.90 | .336 | 1.51 | 8.1 | 5.6 | 8.3 | 68.0 | 61 | 38 | 37 | 8 | 42 | 63 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.53 |