| SP | Kluber, C.Kluber, Corey † >> | 31 | 2017 | R | 96 | 29 | 29 | 10 | 13 | 3.96 | .291 | 1.18 | 7.8 | 2.9 | 10.1 | 197.2 | 171 | 90 | 87 | 22 | 63 | 221 | 6 | 0 | 0 | 3 | 16 | 9 | 4 | 3.30 |
| SP | Buchholz, C.Buchholz, Clay † >> | 29 | 2013 | R | 81 | 28 | 28 | 16 | 6 | 3.15 | .290 | 1.21 | 7.1 | 3.8 | 7.5 | 200.0 | 157 | 74 | 70 | 23 | 84 | 166 | 3 | 0 | 0 | 1 | 20 | 4 | 4 | 4.16 |
| SP | Richards, G.Richards, Garrett >> | 26 | 2014 | R | 74 | 28 | 28 | 13 | 9 | 4.54 | .309 | 1.32 | 7.4 | 4.4 | 8.1 | 178.1 | 147 | 96 | 90 | 19 | 88 | 160 | 1 | 0 | 0 | 0 | 16 | 4 | 11 | 4.14 |
| SP | Clevinger, M.Clevinger, Mike >> | 28 | 2019 | R | 73 | 28 | 28 | 13 | 9 | 3.62 | .289 | 1.18 | 8.0 | 2.7 | 8.9 | 176.2 | 157 | 72 | 71 | 22 | 52 | 174 | 0 | 0 | 0 | 0 | 21 | 6 | 0 | 3.64 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 78 | 0 | 6 | 2 | 3.16 | .265 | 1.05 | 7.5 | 2.0 | 9.6 | 105.1 | 88 | 39 | 37 | 15 | 23 | 112 | 0 | 12 | 2 | 0 | 0 | 3 | 1 | 3.47 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 88 | 72 | 0 | 5 | 4 | 3.38 | .256 | 1.02 | 5.5 | 3.7 | 10.4 | 77.1 | 47 | 30 | 29 | 12 | 32 | 89 | 0 | 16 | 1 | 0 | 0 | 1 | 2 | 4.00 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 62 | 21 | 0 | 0 | 1 | 1.93 | .263 | 1.07 | 7.4 | 2.3 | 6.7 | 23.1 | 19 | 5 | 5 | 1 | 6 | 17 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.87 |
| SP | Giolito, L.Giolito, Lucas >> | 24 | 2019 | R | 72 | 13 | 1 | 2 | 2 | 5.85 | .336 | 1.52 | 10.3 | 3.5 | 9.6 | 64.2 | 73 | 43 | 42 | 16 | 25 | 68 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.30 |