| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 6 | 6 | 3 | 3 | 4.46 | .297 | 1.27 | 8.5 | 3.0 | 9.8 | 36.1 | 34 | 18 | 18 | 3 | 12 | 39 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 2.92 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 6 | 6 | 1 | 3 | 6.47 | .342 | 1.56 | 10.7 | 3.4 | 9.0 | 32.0 | 38 | 23 | 23 | 9 | 12 | 32 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 5.78 |
| SP | Bumgarner, M.Bumgarner, Madison >> | 26 | 2016 | L | 76 | 5 | 5 | 1 | 3 | 4.91 | .348 | 1.57 | 9.3 | 5.0 | 9.3 | 29.1 | 30 | 16 | 16 | 5 | 16 | 30 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.93 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 69 | 5 | 5 | 2 | 2 | 5.00 | .319 | 1.33 | 9.3 | 2.7 | 6.3 | 27.0 | 28 | 15 | 15 | 6 | 8 | 19 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 5.59 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 58 | 5 | 5 | 3 | 1 | 4.26 | .292 | 1.21 | 8.3 | 2.6 | 4.7 | 38.0 | 35 | 18 | 18 | 7 | 11 | 20 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 5.29 |
| RP | Sanchez, A.Sanchez, Aaron >> | 21 | 2014 | R | 91 | 20 | 0 | 1 | 0 | 3.86 | .280 | 1.09 | 6.5 | 3.6 | 5.4 | 25.2 | 18 | 11 | 11 | 4 | 10 | 15 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 5.32 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 82 | 13 | 0 | 0 | 1 | 4.05 | .245 | 0.98 | 4.8 | 4.2 | 9.7 | 13.1 | 7 | 6 | 6 | 1 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.23 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 76 | 12 | 0 | 2 | 0 | 1.56 | .278 | 1.10 | 5.8 | 4.2 | 9.5 | 17.1 | 11 | 3 | 3 | 0 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.47 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 66 | 11 | 0 | 0 | 0 | 6.75 | .333 | 1.50 | 11.0 | 3.0 | 12.0 | 9.1 | 11 | 7 | 7 | 2 | 3 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Neris, H.Neris, Hector >> | 30 | 2019 | R | 38 | 10 | 0 | 0 | 1 | 5.79 | .333 | 1.50 | 12.0 | 2.0 | 7.0 | 9.1 | 12 | 6 | 6 | 1 | 2 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.56 |