| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 92 | 36 | 36 | 15 | 15 | 4.60 | .292 | 1.21 | 8.2 | 2.7 | 8.2 | 248.2 | 227 | 129 | 127 | 44 | 75 | 226 | 5 | 0 | 0 | 1 | 20 | 6 | 1 | 4.46 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 89 | 35 | 35 | 16 | 10 | 3.93 | .311 | 1.32 | 7.7 | 4.2 | 9.5 | 219.2 | 187 | 100 | 96 | 24 | 102 | 232 | 0 | 0 | 0 | 0 | 21 | 8 | 6 | 3.81 |
| SP | Hamels, C.Hamels, Cole † # >> | 28 | 2011 | L | 80 | 34 | 34 | 17 | 9 | 3.99 | .301 | 1.27 | 8.6 | 2.9 | 7.5 | 245.2 | 234 | 111 | 109 | 27 | 78 | 203 | 3 | 0 | 0 | 1 | 21 | 6 | 5 | 3.80 |
| SP | Severino, L.Severino, Luis # >> | 23 | 2017 | R | 73 | 31 | 31 | 10 | 13 | 4.56 | .308 | 1.30 | 8.2 | 3.6 | 9.7 | 187.2 | 170 | 96 | 95 | 25 | 74 | 201 | 0 | 0 | 0 | 0 | 19 | 6 | 1 | 3.87 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 92 | 0 | 7 | 3 | 3.20 | .260 | 1.04 | 6.6 | 2.8 | 11.5 | 112.2 | 82 | 40 | 40 | 11 | 35 | 143 | 0 | 3 | 5 | 0 | 0 | 2 | 2 | 2.71 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 82 | 76 | 0 | 6 | 3 | 2.51 | .288 | 1.17 | 6.5 | 4.1 | 12.3 | 82.1 | 59 | 23 | 23 | 8 | 37 | 112 | 0 | 3 | 4 | 0 | 0 | 4 | 1 | 3.04 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 43 | 0 | 2 | 4 | 4.15 | .293 | 1.25 | 8.0 | 3.3 | 10.3 | 43.1 | 38 | 20 | 20 | 7 | 16 | 49 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3.95 |
| RP | Feliz, N.Feliz, Neftali >> | 22 | 2010 | R | 64 | 19 | 0 | 2 | 0 | 6.38 | .345 | 1.53 | 11.0 | 3.0 | 10.0 | 18.1 | 22 | 13 | 13 | 5 | 6 | 20 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 5.56 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 58 | 25 | 0 | 0 | 1 | 6.84 | .325 | 1.41 | 11.1 | 1.7 | 10.7 | 26.1 | 32 | 21 | 20 | 6 | 5 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.31 |
| CL | Leclerc, J.Leclerc, Jose † >> | 24 | 2018 | R | 88 | 64 | 0 | 5 | 7 | 2.79 | .298 | 1.23 | 5.8 | 5.4 | 11.6 | 67.2 | 43 | 25 | 21 | 9 | 40 | 86 | 0 | 39 | 6 | 0 | 0 | 3 | 1 | 4.10 |
| SP | Porcello, R.Porcello, Rick >> | 27 | 2016 | R | 57 | 9 | 2 | 1 | 2 | 8.57 | .397 | 1.93 | 13.9 | 3.4 | 8.8 | 42.0 | 65 | 40 | 40 | 12 | 16 | 41 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 6.05 |