| SP | Buchholz, C.Buchholz, Clay >> | 29 | 2013 | R | 81 | 33 | 33 | 9 | 16 | 5.70 | .376 | 1.79 | 11.1 | 5.1 | 7.1 | 211.2 | 260 | 138 | 134 | 31 | 119 | 167 | 0 | 0 | 0 | 0 | 12 | 4 | 3 | 5.08 |
| SP | Shields, J.Shields, James # >> | 30 | 2011 | R | 62 | 32 | 32 | 11 | 13 | 4.31 | .313 | 1.35 | 9.0 | 3.1 | 8.3 | 240.1 | 241 | 120 | 115 | 40 | 83 | 220 | 6 | 0 | 0 | 0 | 15 | 5 | 6 | 4.43 |
| SP | Paxton, J.Paxton, James >> | 29 | 2018 | L | 45 | 32 | 32 | 5 | 19 | 6.48 | .365 | 1.68 | 11.4 | 3.7 | 10.1 | 169.1 | 215 | 123 | 122 | 34 | 70 | 189 | 0 | 0 | 0 | 0 | 11 | 7 | 10 | 4.75 |
| SP | Romero, R.Romero, Ricky >> | 26 | 2011 | L | 35 | 31 | 30 | 7 | 16 | 5.34 | .333 | 1.47 | 9.1 | 4.2 | 7.2 | 195.1 | 198 | 121 | 116 | 39 | 90 | 155 | 3 | 0 | 0 | 2 | 15 | 5 | 2 | 5.47 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 80 | 84 | 0 | 5 | 7 | 4.06 | .305 | 1.27 | 7.7 | 3.8 | 9.4 | 99.2 | 85 | 46 | 45 | 17 | 42 | 103 | 0 | 9 | 3 | 0 | 0 | 4 | 3 | 4.55 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 60 | 58 | 0 | 1 | 2 | 4.23 | .294 | 1.23 | 6.0 | 5.2 | 10.3 | 61.2 | 41 | 32 | 29 | 10 | 35 | 70 | 0 | 8 | 2 | 0 | 0 | 1 | 4 | 4.61 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 34 | 2014 | R | 45 | 44 | 0 | 2 | 2 | 5.62 | .335 | 1.49 | 10.5 | 3.1 | 7.0 | 49.2 | 57 | 32 | 31 | 8 | 17 | 38 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.67 |
| RP | Smith, C.Smith, Carson >> | 25 | 2015 | R | 35 | 36 | 0 | 4 | 0 | 4.58 | .369 | 1.70 | 10.6 | 4.8 | 9.5 | 39.1 | 46 | 21 | 20 | 3 | 21 | 41 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.67 |