| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 31 | 31 | 13 | 6 | 2.73 | .271 | 1.08 | 7.1 | 2.7 | 10.3 | 220.2 | 173 | 67 | 67 | 15 | 66 | 252 | 3 | 0 | 0 | 1 | 22 | 7 | 3 | 2.59 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 87 | 29 | 29 | 9 | 6 | 2.87 | .295 | 1.22 | 6.6 | 4.4 | 10.3 | 156.2 | 115 | 51 | 50 | 9 | 76 | 179 | 0 | 0 | 0 | 0 | 8 | 6 | 3 | 3.03 |
| SP | Pepiot, R.Pepiot, Ryan † # >> | 27 | 2025 | R | 76 | 30 | 30 | 12 | 11 | 3.75 | .314 | 1.36 | 8.2 | 4.1 | 10.4 | 170.1 | 154 | 72 | 71 | 17 | 77 | 196 | 0 | 0 | 0 | 0 | 10 | 3 | 8 | 3.41 |
| SP | Springs, J.Springs, Jeffrey >> | 32 | 2025 | L | 62 | 30 | 30 | 8 | 12 | 5.25 | .350 | 1.59 | 10.8 | 3.5 | 7.6 | 161.0 | 194 | 94 | 94 | 18 | 62 | 136 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 3.99 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 59 | 30 | 30 | 5 | 10 | 6.18 | .358 | 1.66 | 11.3 | 3.6 | 6.9 | 161.2 | 203 | 116 | 111 | 20 | 65 | 123 | 1 | 0 | 0 | 1 | 10 | 3 | 4 | 4.35 |
| RP | Suarez, R.Suarez, Robert >> | 34 | 2025 | R | 90 | 77 | 0 | 5 | 7 | 4.17 | .310 | 1.33 | 9.0 | 3.1 | 10.1 | 103.2 | 103 | 49 | 48 | 8 | 35 | 116 | 0 | 4 | 10 | 0 | 0 | 2 | 2 | 2.83 |
| RP | Iglesias, R.Iglesias, Raisel >> | 35 | 2025 | R | 78 | 72 | 0 | 3 | 8 | 4.35 | .326 | 1.42 | 9.6 | 3.2 | 8.9 | 91.0 | 97 | 44 | 44 | 10 | 32 | 90 | 0 | 6 | 8 | 0 | 0 | 3 | 0 | 3.60 |
| RP | Banks, T.Banks, Tanner # >> | 33 | 2025 | L | 67 | 66 | 0 | 6 | 5 | 4.77 | .299 | 1.24 | 8.0 | 3.1 | 8.6 | 83.0 | 74 | 44 | 44 | 5 | 29 | 79 | 0 | 3 | 5 | 0 | 0 | 3 | 2 | 3.04 |
| RP | Rodriguez, M.Rodriguez, Manuel >> | 28 | 2025 | R | 57 | 53 | 0 | 5 | 2 | 4.50 | .325 | 1.44 | 9.7 | 3.3 | 6.8 | 54.0 | 58 | 27 | 27 | 7 | 20 | 41 | 0 | 7 | 2 | 0 | 0 | 0 | 2 | 4.28 |
| SP | Bibee, T.Bibee, Tanner >> | 26 | 2025 | R | 51 | 4 | 1 | 1 | 0 | 3.12 | .316 | 1.38 | 9.0 | 4.5 | 6.8 | 8.2 | 8 | 3 | 3 | 2 | 4 | 6 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 6.25 |
| SP | Kremer, D.Kremer, Dean >> | 29 | 2025 | R | 50 | 25 | 0 | 4 | 2 | 5.49 | .349 | 1.56 | 10.8 | 3.3 | 7.0 | 41.0 | 49 | 25 | 25 | 6 | 15 | 32 | 0 | 3 | 2 | 0 | 0 | 2 | 5 | 4.59 |