| SP | Skubal, T.Skubal, Tarik # >> | 28 | 2025 | L | 100 | 8 | 8 | 2 | 5 | 4.05 | .307 | 1.33 | 10.2 | 1.9 | 11.4 | 53.1 | 60 | 24 | 24 | 10 | 11 | 67 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.55 |
| SP | Rasmussen, D.Rasmussen, Drew >> | 29 | 2025 | R | 83 | 8 | 8 | 2 | 3 | 4.91 | .323 | 1.41 | 8.4 | 4.3 | 5.7 | 44.0 | 41 | 24 | 24 | 6 | 21 | 28 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.00 |
| SP | Williams, G.Williams, Gavin >> | 25 | 2025 | R | 64 | 7 | 7 | 3 | 0 | 4.46 | .331 | 1.46 | 8.8 | 4.5 | 11.6 | 38.1 | 37 | 19 | 19 | 2 | 19 | 49 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 2.68 |
| SP | Bibee, T.Bibee, Tanner >> | 26 | 2025 | R | 51 | 7 | 7 | 3 | 3 | 3.75 | .287 | 1.21 | 8.1 | 2.8 | 8.3 | 48.0 | 43 | 20 | 20 | 5 | 15 | 44 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 3.46 |
| RP | Okert, S.Okert, Steven >> | 33 | 2025 | L | 97 | 21 | 0 | 0 | 0 | 5.14 | .300 | 1.25 | 8.7 | 2.6 | 10.0 | 28.0 | 27 | 16 | 16 | 7 | 8 | 31 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.00 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 87 | 21 | 0 | 2 | 0 | 3.90 | .274 | 1.13 | 7.5 | 2.7 | 6.3 | 30.0 | 25 | 13 | 13 | 3 | 9 | 21 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.80 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 69 | 16 | 0 | 1 | 3 | 7.27 | .358 | 1.62 | 13.8 | 1.1 | 8.5 | 17.1 | 26 | 17 | 14 | 6 | 2 | 16 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 6.24 |
| RP | Rodriguez, M.Rodriguez, Manuel >> | 28 | 2025 | R | 57 | 14 | 0 | 1 | 1 | 4.67 | .288 | 1.15 | 6.9 | 3.7 | 9.5 | 17.1 | 13 | 9 | 9 | 4 | 7 | 18 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 5.35 |
| RP | Romero, J.Romero, JoJo >> | 28 | 2025 | L | 49 | 12 | 0 | 2 | 1 | 6.75 | .353 | 1.64 | 8.4 | 7.1 | 7.7 | 14.2 | 13 | 11 | 11 | 1 | 11 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.57 |
| SP | Giolito, L.Giolito, Lucas >> | 30 | 2025 | R | 41 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |