| SP | Skenes, P.Skenes, Paul >> | 23 | 2025 | R | 93 | 20 | 20 | 10 | 3 | 3.18 | .287 | 1.16 | 7.5 | 3.0 | 9.1 | 124.1 | 103 | 44 | 44 | 9 | 41 | 125 | 1 | 0 | 0 | 1 | 12 | 6 | 1 | 3.06 |
| SP | Glasnow, T.Glasnow, Tyler † >> | 31 | 2025 | R | 87 | 19 | 19 | 9 | 2 | 2.74 | .289 | 1.17 | 6.9 | 3.7 | 8.4 | 101.2 | 77 | 31 | 31 | 6 | 42 | 94 | 0 | 0 | 0 | 0 | 5 | 5 | 3 | 3.31 |
| SP | Kirby, G.Kirby, George >> | 27 | 2025 | R | 60 | 19 | 19 | 8 | 6 | 5.79 | .362 | 1.65 | 11.0 | 4.0 | 10.1 | 91.2 | 111 | 60 | 59 | 14 | 40 | 102 | 0 | 0 | 0 | 0 | 4 | 5 | 4 | 4.24 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 81 | 19 | 19 | 4 | 6 | 5.99 | .354 | 1.62 | 11.1 | 3.6 | 7.9 | 106.2 | 131 | 74 | 71 | 18 | 42 | 93 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.70 |
| CL | Svanson, M.Svanson, Matt † >> | 26 | 2025 | R | 97 | 44 | 0 | 5 | 1 | 1.89 | .247 | 0.90 | 4.8 | 3.4 | 9.4 | 47.2 | 25 | 10 | 10 | 4 | 18 | 49 | 0 | 31 | 2 | 0 | 0 | 4 | 2 | 3.43 |
| RP | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 91 | 45 | 0 | 5 | 2 | 4.55 | .359 | 1.63 | 10.1 | 4.6 | 7.9 | 55.1 | 62 | 28 | 28 | 9 | 28 | 48 | 0 | 2 | 3 | 0 | 0 | 3 | 0 | 5.07 |
| RP | Estevez, C.Estevez, Carlos >> | 32 | 2025 | R | 67 | 35 | 0 | 2 | 0 | 1.54 | .241 | 0.90 | 4.8 | 3.3 | 9.7 | 41.0 | 22 | 7 | 7 | 2 | 15 | 44 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 2.73 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 81 | 31 | 0 | 0 | 2 | 4.78 | .304 | 1.28 | 7.0 | 4.5 | 9.3 | 32.0 | 25 | 17 | 17 | 4 | 16 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.16 |
| SP | Bello, B.Bello, Brayan >> | 26 | 2025 | R | 53 | 18 | 0 | 9 | 0 | 4.50 | .365 | 1.69 | 11.5 | 3.7 | 7.6 | 58.0 | 74 | 31 | 29 | 6 | 24 | 49 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.00 |