| SP | Galarraga, A.Galarraga, Armando >> | 28 | 2008 | R | 80 | 28 | 28 | 14 | 9 | 4.02 | .306 | 1.28 | 7.5 | 4.0 | 7.1 | 177.0 | 148 | 83 | 79 | 20 | 78 | 139 | 2 | 0 | 0 | 1 | 18 | 8 | 1 | 4.36 |
| SP | Verlander, J.Verlander, Justin >> | 27 | 2010 | R | 81 | 28 | 28 | 12 | 9 | 3.86 | .300 | 1.25 | 8.3 | 2.9 | 7.4 | 196.0 | 181 | 88 | 84 | 20 | 64 | 161 | 3 | 0 | 0 | 0 | 19 | 7 | 7 | 3.77 |
| SP | Bergmann, J.Bergmann, Jay >> | 29 | 2007 | R | 60 | 28 | 28 | 9 | 8 | 3.92 | .302 | 1.28 | 8.4 | 3.1 | 6.7 | 170.0 | 158 | 76 | 74 | 15 | 59 | 126 | 0 | 0 | 0 | 0 | 14 | 4 | 6 | 3.78 |
| SP | Perez, O.Perez, Oliver # >> | 29 | 2007 | L | 59 | 27 | 27 | 9 | 7 | 4.29 | .320 | 1.36 | 9.2 | 3.1 | 8.4 | 167.2 | 170 | 91 | 80 | 24 | 58 | 156 | 0 | 0 | 0 | 0 | 14 | 9 | 8 | 4.20 |
| SP | Bonderman, J.Bonderman, Jeremy # >> | 28 | 2005 | R | 38 | 27 | 27 | 9 | 6 | 4.76 | .294 | 1.25 | 8.9 | 2.4 | 7.8 | 162.2 | 160 | 87 | 86 | 18 | 43 | 141 | 0 | 0 | 0 | 0 | 12 | 0 | 9 | 3.50 |
| RP | Zumaya, J.Zumaya, Joel >> | 26 | 2006 | R | 91 | 73 | 0 | 5 | 3 | 4.55 | .344 | 1.54 | 9.3 | 4.5 | 10.3 | 99.0 | 102 | 56 | 50 | 8 | 50 | 113 | 0 | 12 | 6 | 0 | 0 | 4 | 6 | 3.40 |
| RP | Percival, T.Percival, Troy >> | 41 | 2007 | R | 68 | 62 | 0 | 3 | 6 | 5.13 | .322 | 1.37 | 7.5 | 4.9 | 6.0 | 66.2 | 55 | 39 | 38 | 11 | 36 | 44 | 0 | 7 | 7 | 0 | 0 | 4 | 8 | 5.65 |
| RP | Mathis, D.Mathis, Doug # >> | 27 | 2009 | R | 55 | 48 | 0 | 6 | 7 | 5.35 | .318 | 1.34 | 10.0 | 2.2 | 6.0 | 70.2 | 78 | 42 | 42 | 9 | 17 | 47 | 0 | 9 | 5 | 0 | 0 | 4 | 0 | 4.23 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 34 | 2010 | R | 51 | 20 | 0 | 2 | 1 | 2.05 | .241 | 0.91 | 5.7 | 2.5 | 8.2 | 22.0 | 14 | 5 | 5 | 1 | 6 | 20 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 2.73 |
| RP | Spurling, C.Spurling, Chris >> | 33 | 2005 | R | 50 | 23 | 0 | 2 | 2 | 5.47 | .368 | 1.71 | 13.8 | 1.7 | 7.6 | 26.1 | 40 | 16 | 16 | 2 | 5 | 22 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 3.00 |
| RP | Feldman, S.Feldman, Scott >> | 27 | 2006 | R | 47 | 26 | 0 | 1 | 3 | 6.91 | .333 | 1.43 | 10.0 | 3.0 | 8.0 | 27.1 | 30 | 21 | 21 | 4 | 9 | 24 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.37 |
| SP | Porcello, R.Porcello, Rick >> | 21 | 2009 | R | 32 | 17 | 0 | 2 | 3 | 6.30 | .371 | 1.74 | 11.2 | 4.6 | 6.4 | 65.2 | 81 | 52 | 46 | 9 | 33 | 46 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 5.00 |