| SP | Harden, R.Harden, Rich >> | 30 | 2008 | R | 92 | 34 | 34 | 11 | 9 | 4.45 | .316 | 1.35 | 8.2 | 3.9 | 9.6 | 196.1 | 179 | 97 | 97 | 25 | 86 | 209 | 0 | 0 | 0 | 0 | 14 | 7 | 4 | 3.95 |
| SP | Zambrano, C.Zambrano, Carlos >> | 30 | 2005 | R | 94 | 34 | 34 | 14 | 14 | 4.15 | .307 | 1.29 | 8.0 | 3.7 | 7.3 | 238.2 | 211 | 117 | 110 | 35 | 97 | 194 | 5 | 0 | 0 | 1 | 19 | 9 | 5 | 4.62 |
| SP | Dempster, R.Dempster, Ryan >> | 34 | 2008 | R | 54 | 32 | 32 | 12 | 12 | 5.58 | .321 | 1.41 | 9.1 | 3.6 | 7.9 | 185.1 | 187 | 115 | 115 | 30 | 74 | 162 | 0 | 0 | 0 | 0 | 15 | 2 | 5 | 4.59 |
| CL | Marmol, C.Marmol, Carlos >> | 29 | 2007 | R | 100 | 70 | 0 | 3 | 10 | 4.11 | .319 | 1.35 | 8.2 | 3.9 | 9.6 | 81.0 | 74 | 38 | 37 | 6 | 35 | 86 | 0 | 36 | 5 | 0 | 0 | 5 | 8 | 3.32 |
| SU | Wuertz, M.Wuertz, Michael >> | 33 | 2009 | R | 85 | 67 | 0 | 0 | 9 | 6.78 | .354 | 1.65 | 10.9 | 3.9 | 9.8 | 65.0 | 79 | 50 | 49 | 8 | 28 | 71 | 0 | 1 | 6 | 0 | 0 | 0 | 4 | 3.71 |
| RP | Guzman, A.Guzman, Angel >> | 30 | 2009 | R | 80 | 89 | 0 | 4 | 2 | 3.53 | .268 | 1.10 | 6.8 | 3.1 | 7.0 | 99.1 | 75 | 40 | 39 | 9 | 34 | 77 | 0 | 0 | 4 | 0 | 0 | 0 | 2 | 3.66 |
| RP | Marshall, S.Marshall, Sean >> | 29 | 2010 | L | 84 | 97 | 0 | 6 | 2 | 5.18 | .312 | 1.34 | 9.3 | 2.7 | 11.1 | 80.0 | 83 | 47 | 46 | 11 | 24 | 99 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 3.29 |
| RP | Aardsma, D.Aardsma, David >> | 30 | 2010 | R | 81 | 75 | 0 | 4 | 4 | 4.74 | .327 | 1.46 | 8.4 | 4.7 | 9.5 | 74.0 | 69 | 40 | 39 | 11 | 39 | 78 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 4.41 |