| SP | Harden, R.Harden, Rich >> | 29 | 2008 | R | 98 | 28 | 28 | 6 | 10 | 3.75 | .313 | 1.35 | 7.3 | 4.9 | 8.9 | 170.1 | 138 | 72 | 71 | 16 | 92 | 168 | 0 | 0 | 0 | 0 | 11 | 3 | 4 | 3.92 |
| SP | Zambrano, C.Zambrano, Carlos >> | 29 | 2005 | R | 95 | 27 | 27 | 9 | 9 | 4.16 | .303 | 1.25 | 7.6 | 3.7 | 7.9 | 197.0 | 166 | 95 | 91 | 15 | 80 | 173 | 2 | 0 | 0 | 0 | 15 | 11 | 7 | 3.62 |
| SP | Dempster, R.Dempster, Ryan >> | 33 | 2008 | R | 67 | 27 | 27 | 14 | 9 | 3.79 | .280 | 1.15 | 7.4 | 3.0 | 7.5 | 183.0 | 150 | 78 | 77 | 16 | 61 | 152 | 0 | 0 | 0 | 0 | 19 | 3 | 1 | 3.52 |
| CL | Marmol, C.Marmol, Carlos >> | 28 | 2007 | R | 99 | 54 | 0 | 5 | 3 | 3.77 | .306 | 1.33 | 7.9 | 4.1 | 8.5 | 57.1 | 50 | 24 | 24 | 8 | 26 | 54 | 0 | 33 | 8 | 0 | 0 | 0 | 4 | 4.30 |
| SU | Wuertz, M.Wuertz, Michael >> | 32 | 2009 | R | 95 | 51 | 0 | 4 | 4 | 3.55 | .330 | 1.44 | 7.2 | 5.9 | 11.9 | 50.2 | 40 | 20 | 20 | 4 | 33 | 66 | 0 | 2 | 4 | 0 | 0 | 2 | 1 | 3.50 |
| RP | Guzman, A.Guzman, Angel >> | 29 | 2009 | R | 92 | 77 | 0 | 6 | 3 | 3.74 | .304 | 1.31 | 7.5 | 4.3 | 5.6 | 79.1 | 66 | 35 | 33 | 7 | 38 | 49 | 0 | 3 | 3 | 0 | 0 | 0 | 4 | 4.35 |
| RP | Marshall, S.Marshall, Sean >> | 28 | 2010 | L | 73 | 69 | 0 | 0 | 1 | 3.83 | .330 | 1.48 | 8.6 | 4.8 | 8.8 | 49.1 | 47 | 22 | 21 | 4 | 26 | 48 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.69 |
| RP | Aardsma, D.Aardsma, David >> | 29 | 2010 | R | 70 | 51 | 0 | 3 | 3 | 4.93 | .347 | 1.57 | 9.7 | 4.5 | 11.1 | 38.1 | 41 | 21 | 21 | 7 | 19 | 47 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.50 |