| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 7 | 7 | 2 | 4 | 3.40 | .317 | 1.37 | 9.4 | 3.0 | 10.5 | 42.1 | 44 | 21 | 16 | 4 | 14 | 49 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 2.98 |
| SP | Crochet, G.Crochet, Garrett >> | 26 | 2025 | L | 89 | 6 | 6 | 4 | 1 | 4.72 | .318 | 1.34 | 9.0 | 3.2 | 9.8 | 34.1 | 34 | 18 | 18 | 5 | 12 | 37 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 3.97 |
| SP | Cameron, N.Cameron, Noah >> | 25 | 2025 | L | 79 | 6 | 6 | 5 | 1 | 3.19 | .308 | 1.28 | 9.5 | 2.3 | 9.3 | 36.2 | 38 | 13 | 13 | 3 | 9 | 37 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 2.94 |
| SP | Castillo, L.Castillo, Luis >> | 32 | 2025 | R | 62 | 6 | 6 | 0 | 1 | 9.58 | .426 | 2.23 | 16.2 | 4.5 | 5.4 | 20.2 | 36 | 22 | 22 | 8 | 10 | 12 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 8.50 |
| SP | Kershaw, C.Kershaw, Clayton >> | 37 | 2025 | L | 57 | 9 | 6 | 1 | 1 | 3.86 | .295 | 1.26 | 9.8 | 1.7 | 7.6 | 32.2 | 35 | 14 | 14 | 6 | 6 | 27 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 4.31 |
| RP | Suarez, R.Suarez, Robert >> | 34 | 2025 | R | 92 | 17 | 0 | 0 | 1 | 3.38 | .286 | 1.13 | 9.0 | 1.4 | 9.0 | 26.2 | 26 | 10 | 10 | 4 | 4 | 26 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 3.69 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 84 | 20 | 0 | 2 | 3 | 7.88 | .287 | 1.13 | 7.1 | 3.0 | 12.0 | 24.0 | 19 | 21 | 21 | 6 | 8 | 32 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.83 |
| RP | Henriquez, R.Henriquez, Ronny >> | 25 | 2025 | R | 78 | 17 | 0 | 0 | 0 | 5.00 | .379 | 1.83 | 9.0 | 7.5 | 11.0 | 18.0 | 18 | 10 | 10 | 2 | 15 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.50 |
| RP | Santillan, T.Santillan, Tony >> | 28 | 2025 | R | 73 | 13 | 0 | 1 | 0 | 4.32 | .286 | 1.20 | 7.3 | 3.9 | 11.3 | 16.2 | 13 | 8 | 8 | 2 | 7 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.44 |
| SP | Bello, B.Bello, Brayan >> | 26 | 2025 | R | 55 | 8 | 0 | 1 | 3 | 6.14 | .371 | 1.73 | 10.2 | 5.3 | 8.6 | 22.0 | 25 | 15 | 15 | 3 | 13 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.77 |