| SP | Skubal, T.Skubal, Tarik $$ >> | 28 | 2025 | L | 100 | 35 | 35 | 11 | 12 | 3.75 | .286 | 1.18 | 8.0 | 2.6 | 9.7 | 221.0 | 197 | 98 | 92 | 20 | 64 | 238 | 0 | 0 | 0 | 0 | 22 | 5 | 2 | 2.96 |
| SP | Burrows, M.Burrows, Mike # >> | 25 | 2025 | R | 58 | 31 | 31 | 4 | 10 | 5.09 | .330 | 1.46 | 9.4 | 3.8 | 9.9 | 123.2 | 129 | 72 | 70 | 28 | 52 | 135 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 5.08 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 79 | 83 | 0 | 4 | 1 | 3.01 | .282 | 1.14 | 7.2 | 3.1 | 11.5 | 92.2 | 74 | 31 | 31 | 10 | 32 | 118 | 0 | 6 | 5 | 0 | 0 | 3 | 13 | 2.99 |
| RP | Strahm, M.Strahm, Matt >> | 33 | 2025 | L | 73 | 113 | 0 | 5 | 5 | 4.02 | .309 | 1.26 | 8.0 | 3.4 | 10.5 | 100.2 | 89 | 51 | 45 | 18 | 38 | 117 | 0 | 3 | 4 | 0 | 0 | 8 | 2 | 4.38 |
| RP | Koenig, J.Koenig, Jared >> | 31 | 2025 | L | 57 | 51 | 0 | 2 | 1 | 3.12 | .293 | 1.22 | 8.4 | 2.7 | 11.1 | 43.1 | 40 | 17 | 15 | 5 | 13 | 53 | 0 | 4 | 4 | 0 | 0 | 1 | 1 | 3.02 |
| SP | Castillo, L.Castillo, Luis >> | 32 | 2025 | R | 62 | 57 | 0 | 11 | 10 | 4.35 | .335 | 1.48 | 9.6 | 3.7 | 8.8 | 99.1 | 106 | 53 | 48 | 9 | 41 | 97 | 0 | 8 | 3 | 0 | 0 | 3 | 6 | 3.56 |